Angiotensin Ii 2.5 mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 2.5 mg

Reference Brands: Giapreza (USA)

Category: Critical Care

Angiotensin Ii is a Critical Care product available as Injection in strengths 2.5 mg. It corresponds to the reference brand Giapreza (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Angiotensin II is a peptide endocrine hormone and a key component of the renin–angiotensin–aldosterone system (RAAS), an essential regulatory system responsible for maintaining blood pressure, vascular tone, and fluid balance. It is derived from angiotensinogen, an alpha-globulin prohormone synthesized primarily in the liver and circulated in plasma. Through a cascade of enzymatic reactions, angiotensin II is formed and acts as a potent vasoconstrictor.

Clinically, angiotensin II increases blood pressure by causing direct vasoconstriction of blood vessels and by stimulating the release of aldosterone from the adrenal cortex. Aldosterone promotes sodium and water retention by the kidneys, further contributing to increased intravascular volume and blood pressure stabilization.

Angiotensin II has received approval from the United States Food and Drug Administration (FDA) for use in adult patients with septic or distributive shock who remain hypotensive despite adequate fluid resuscitation and conventional vasopressor therapy. It is administered intravenously in controlled critical care settings.

Due to its targeted mechanism of action, angiotensin II plays an important role in modern shock management protocols and is utilized by multidisciplinary healthcare teams in intensive care environments to support hemodynamic stability in critically ill patients.