Fludrocortisone Acetate Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 0.1 mg
Reference Brands: Florinef (USA)
Category:
Immune Disorder
Fludrocortisone Acetate is available in Tablets
and strengths such as 0.1 mg.
Sourced from GMP-certified and ISO-compliant manufacturers, this API meets
global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical
formulation and commercial manufacturing, Fludrocortisone Acetate is supplied in
bulk quantities with complete regulatory support including DMF, COA, and MSDS.
|
Technical Specifications & Supply Details
|
| Lead Time |
7 to 60 days (depending on batch size & schedule) |
| MOQ |
As per manufacturer’s batch size |
| COA |
Available with every batch |
| Regulatory Dossier / DMF |
Available upon request |
| Export Documentation |
FSC, COA, Manufacturing License, Product Permission |
| Standards |
IP, BP, USP |
| Certifications |
WHO-GMP, EU-GMP, USFDA (as applicable) |
Fludrocortisone Acetate can be exported to over 30 countries across Asia, Africa, Europe,
and Latin America. Flexible packaging, competitive pricing, and a verified supplier
network make Pharmatradz a trusted sourcing partner for pharmaceutical companies
and contract manufacturers worldwide.
Product Description:
Fludrocortisone acetate is the acetate salt of a synthetic fluorinated corticosteroid with potent mineralocorticoid activity and additional anti-inflammatory and antiallergic properties. It acts as a glucocorticoid-receptor agonist by binding to cytoplasmic receptors, followed by translocation of the drug–receptor complex into the cell nucleus. This process initiates transcription of glucocorticoid-responsive genes, including lipocortins, which inhibit phospholipase A2 (PLA2). Inhibition of PLA2 prevents the release of arachidonic acid, thereby reducing the formation of pro-inflammatory eicosanoids such as prostaglandins and leukotrienes that play a key role in inflammatory and allergic responses.
In addition to its glucocorticoid effects, fludrocortisone acetate exhibits strong mineralocorticoid-receptor agonist activity. It enhances sodium reabsorption and water retention while promoting potassium and hydrogen ion excretion in the distal renal tubules and collecting ducts. These actions help regulate electrolyte balance and maintain blood pressure.
Fludrocortisone acetate, marketed under the brand name Florinef and as generics, is primarily used in the management of adrenal insufficiency, congenital adrenal hyperplasia, and postural (orthostatic) hypotension. It is administered orally and is most commonly prescribed in combination with hydrocortisone for adrenal replacement therapy.
Disclaimer: By continuing to browse, you agree to the terms of use of this website and the Trade Marks displayed, in compliance with the provisions of the Trademark Act, 1999, Section 30 and 30(1) under 'Fair use.'
The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Back to Listing