Berotralstat Hydrochloride 150 mg,110 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 150 mg,110 mg

Reference Brands: Orladeyo (USA)

Category: Immune Disorder

Berotralstat Hydrochloride is a Immune Disorder product available as Tablets in strengths 150 mg,110 mg. It corresponds to the reference brand Orladeyo (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Berotralstat, marketed under the brand name Orladeyo, is an oral plasma kallikrein inhibitor used for the prophylactic treatment of hereditary angioedema (HAE) in adults and adolescents aged 12 years and older. HAE is a rare genetic disorder characterized by recurrent episodes of severe swelling in various parts of the body, including the face, extremities, gastrointestinal tract, and airway. These attacks can be painful, debilitating, and potentially life-threatening when the airway is involved.

By selectively inhibiting plasma kallikrein, berotralstat reduces the excessive production of bradykinin, a key mediator responsible for the swelling and pain experienced during HAE attacks. This mechanism helps prevent the onset of HAE episodes, improving patient quality of life and providing a convenient, once-daily oral therapy compared to injectable alternatives. Berotralstat represents a targeted approach for long-term disease management, offering patients effective prophylaxis against recurrent hereditary angioedema attacks.