Belumosudil 200 mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 200 mg
Reference Brands: Rezurock (USA)
Category: Immune Disorder
Belumosudil is a Immune Disorder product available as Tablets in strengths 200 mg. It corresponds to the reference brand Rezurock (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Belumosudil, marketed under the brand name Rezurock, is an oral targeted therapy used for the treatment of chronic graft-versus-host disease (cGVHD), a serious immune-mediated complication that can occur following allogeneic stem cell transplantation. It belongs to the class of serine/threonine kinase inhibitors and is specifically designed to inhibit Rho-associated coiled-coil kinase 2 (ROCK2).
ROCK2 plays a central role in regulating immune cell signaling pathways involved in inflammation and fibrosis. By selectively inhibiting ROCK2, belumosudil helps rebalance pro- and anti-inflammatory immune responses, thereby reducing chronic immune activation and tissue damage associated with cGVHD. This targeted mechanism allows for immune modulation without broad immunosuppression.
Preclinical and cellular studies have shown that belumosudil also influences several key biological pathways, including oxidative phosphorylation, WNT signaling, angiogenesis, and KRAS signaling. These additional effects may contribute to its therapeutic benefits in controlling immune dysregulation and fibrotic processes.
Administered orally, Rezurock provides a convenient treatment option for patients with limited alternatives after failure of prior systemic therapies. Its targeted approach represents an important advancement in the management of chronic graft-versus-host disease, offering improved disease control and quality of life for affected patients.
Belumosudil — third party manufacturing & bulk supply
Belumosudil 200 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Belumosudil listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Belumosudil →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Belumosudil is used for the treatment of adult and pediatric patients aged 12 years and older with chronic graft-versus-host disease (cGVHD) after failure of at least two prior lines of systemic therapy.
Belumosudil is a small-molecule, synthetic ROCK2 inhibitor designed to regulate immune and fibrotic pathways.
The trade name of belumosudil is Rezurock.
Belumosudil (Rezurock) is developed and marketed by Kadmon Pharmaceuticals, a subsidiary of Sanofi.
The generic name of Belumosudil is belumosudil.
The brand name of Belumosudil is Rezurock.
Belumosudil (Rezurock) is manufactured for Kadmon Pharmaceuticals (Sanofi) in the United States through FDA-approved pharmaceutical manufacturing facilities.
Related Products
Etrasimod Arginine
Strength:
2 mg, 4 mg, 6 mg
Form: Tablets
Reference Brands: Velsipity (USA)
View Details
Fostamatinib Disodium
Strength:
100 mg, 150 mg
Form: Tablets
Reference Brands: Tavalisse (USA)
View Details
Quick Response Guaranteed | Verified Suppliers
