Doxapram Hydrochloride 10 mg/mL, 20 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 10 mg/mL, 20 mg/mL

Reference Brands: Dopram (USA/EU)

Category: Critical Care

Doxapram Hydrochloride is a Critical Care product available as Injection in strengths 10 mg/mL, 20 mg/mL. It corresponds to the reference brand Dopram (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Doxapram hydrochloride is a potent respiratory stimulant used in intensive care settings to manage patients with respiratory failure or acute respiratory depression. It is particularly useful in cases where respiratory depression results from drug overdose, such as opioids, and when standard treatments like naloxone are insufficient. Doxapram acts on the chemoreceptors in the carotid bodies and the respiratory center in the brainstem to increase both the rate and depth of breathing, providing rapid improvement in ventilation.

In addition to its respiratory stimulant effects, doxapram has been shown to effectively suppress postoperative shivering, performing similarly to pethidine in this regard. The medication is administered intravenously under strict medical supervision due to its potent effects and potential cardiovascular side effects. Doxapram is used in both human critical care and selected veterinary applications to stimulate respiration when required, making it a versatile agent in acute medical management.