Clotrimazole Vaginal Tablet 100 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 100 mg

Reference Brands: Femcare (USA), Mycelex (USA), Canesten (EU), Gyne-Lotrimin(USA)

Category: Anti-fungal

Clotrimazole vaginal (for use in the vagina) is used to treat vaginal candida (yeast) infections.

Product Description:

Clotrimazole vaginal tablets deliver an imidazole antifungal directly to the site of infection. The tablet dissolves in vaginal moisture, releasing drug that blocks ergosterol synthesis in Candida cell membranes. Local delivery means high concentration where it is needed with almost no systemic absorption, which is why it is usable in pregnancy, where oral fluconazole is avoided.

It is used for vulvovaginal candidiasis, as a course of one, three or six nights depending on the strength; the 100 mg tablet is typically used for six nights or two tablets for three. Cure rates are comparable to a single oral fluconazole dose, and the choice usually comes down to preference — some women prefer a tablet they swallow, others prefer to avoid a systemic drug. An accompanying cream for external itch is commonly supplied. Local burning and irritation are the common complaints. The product can weaken latex condoms and diaphragms.

Sourcing notes. Off patent and over the counter in many markets. Vaginal tablets are a distinct manufacturing competence — the tablet must disintegrate reliably in a low-moisture environment, which is the critical quality attribute. Applicator design and whether an external cream is included define the pack.