Metronidazole / Miconazole nitrate bulk supplier for pharma manufacturers

Metronidazole / Miconazole Nitrate Suppliers & Bulk Manufacturers

Available Forms: Vaginal suppository

Available Strengths: 500 mg + 100 mg / 750mg+200mg

Reference Brands: Invel (USA/EU), Trimic, Inserdin, Ovulomix (LATAM)

METRONIDAZOLE+MICONAZOLE is a combination medicine used to treat vaginal infections. Vaginal infection is the infection of the vagina and vulva (tissue at the opening of the vagina), which occurs due to the overgrowth of bacteria and fungi. Vaginal infection can cause inflammation, itchiness, thick discharge, change in colour of the discharge, burning sensation or pain during urination, vaginal bleeding or spotting, and pain during intercourse.

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Product Description:

Metronidazole and miconazole nitrate combination is widely used for the treatment of mixed vaginal infections, including bacterial vaginosis, candidiasis, and other forms of vaginitis caused by bacteria, fungi, and protozoa. This dual-action therapy combines metronidazole, an antimicrobial agent effective against anaerobic bacteria and protozoa, with miconazole nitrate, an antifungal agent that targets Candida species. Together, these active ingredients provide broad-spectrum coverage for common vaginal pathogens.

Clinical studies have shown significant improvement in both symptoms and clinical signs of vaginitis following treatment with this combination therapy. The overall clinical cure rate has been reported to be approximately 87.7%. Laboratory evaluations also demonstrate strong effectiveness, with cure rates of about 81.8% based on microscopy and 73.9% according to Candida albicans culture results. In cases of bacterial vaginosis, the treatment achieved a cure rate of around 75%, while cultures of Gardnerella vaginalis became negative in approximately 63.6% of treated patients.

The medication is generally well tolerated and provides an effective therapeutic option for managing mixed vaginal infections, helping restore the normal vaginal microbial balance and relieve symptoms such as discharge, itching, and irritation.

Metronidazole / Miconazole Nitrate — third party manufacturing & bulk supply

Metronidazole / Miconazole Nitrate is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Metronidazole / Miconazole Nitrate is supplied as Vaginal suppository — a dosage form priced by order value, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Metronidazole / Miconazole Nitrate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Metronidazole + Miconazole nitrate is used to treat mixed infections caused by bacteria and fungi, commonly in skin and mucosal areas. It helps reduce inflammation, eliminates harmful bacteria, and stops fungal growth, providing relief from itching, redness, irritation, and discharge.

This combination is made from two active ingredients: metronidazole, a nitroimidazole antibacterial and antiprotozoal agent, and miconazole nitrate, an imidazole antifungal compound that inhibits ergosterol synthesis in fungal cell membranes.

The combination is marketed under various trade names depending on region and manufacturer, including Invel, Trimic, and Inserdin.

Multiple pharmaceutical companies manufacture this combination, including global and Indian generic manufacturers producing antibacterial–antifungal combination products.

The generic name is metronidazole and miconazole nitrate.

Invel ,Trimic, Inserdin.

This combination is manufactured in countries such as the USA, EU, and India by approved pharmaceutical companies producing creams, gels, or suppositories.