Clotiazepam 5mg, 10mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 5mg, 10mg

Reference Brands: -

Category: Neurology

Clotiazepam is a thienodiazepine-class anxiolytic used for the short-term management of anxiety and insomnia. It works by enhancing GABA activity in the central nervous system, producing calming, sedative, and muscle-relaxant effects.

Product Description:

Clotiazepam is a thienodiazepine, a benzodiazepine analogue in which the benzene ring is replaced by thiophene. It acts at the same GABA-A receptor site as classical benzodiazepines, with a short half-life of roughly four to six hours. The short half-life gives it a relatively clean offset, which is why it has been used for daytime anxiety where residual next-day sedation would be a problem, and for sleep-onset difficulty linked to anxiety.

Clinical experience is narrower than for diazepam or alprazolam, and the comparative evidence base is small. Dependence, tolerance and withdrawal behave as with other benzodiazepines, and short half-life agents tend to produce more marked interdose rebound and a sharper withdrawal syndrome than long half-life ones, so tapering matters. Additive respiratory depression with opioids and alcohol applies.

Sourcing notes. Clotiazepam is a Schedule IV psychotropic under the 1971 UN Convention, so every cross-border shipment requires an import authorisation from the receiving country and an export authorisation from the supplier. It is registered in a limited set of markets — France, Italy and Japan among them — and not in the US or UK. Supplier base and registration rather than cost define availability. Confirm the destination market registers it before quoting at all.