Capivasertib 160 mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 160 mg
Reference Brands: Truqap (USA)
Category: Oncology Cancer Care
Capivasertib 160 mg tablets are an AKT inhibitor used with fulvestrant for hormone receptor-positive, HER2-negative advanced breast cancer with PIK3CA, AKT1 or PTEN changes. It is taken twice daily, four days on and three days off. It is made by AstraZeneca as Truqap and is a patented innovator product. Supply is through authorised distribution or named-patient import; ask us which route fits your country.
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Product Description:
Capivasertib, also known by the brand name Truqap, is an oral targeted anticancer therapy used in combination with fulvestrant for the treatment of adults with hormone receptor-positive, HER2-negative advanced or metastatic breast cancer. It is specifically indicated for patients whose disease has progressed during or after prior hormone therapy and who have genetic alterations in the PIK3CA, AKT1, or PTEN genes.
Capivasertib works by selectively inhibiting AKT, a key protein involved in cell signaling pathways that regulate cancer cell growth, survival, and metabolism. By blocking AKT activity, capivasertib disrupts these pathways, helping to slow tumor growth and potentially induce cancer cell death. It belongs to the class of kinase inhibitors and represents an important advancement in precision oncology.
The drug is administered orally under specialist supervision and is being actively studied for use in other cancer types where AKT pathway abnormalities play a role. Capivasertib’s targeted mechanism allows for a more personalized treatment approach, offering improved outcomes for patients with specific molecular profiles while supporting long-term disease control in advanced breast cancer.
How Capivasertib is supplied today, and licensing ahead of patent expiry
Frequently Asked Questions
Capivasertib is used in combination with endocrine therapy to treat adults with hormone receptor-positive, HER2-negative advanced or metastatic breast cancer that has specific AKT pathway alterations.
Capivasertib is a small-molecule synthetic AKT inhibitor designed to block intracellular signaling pathways involved in cancer cell growth and survival.
The trade name is Truqap.
Capivasertib (Truqap) is manufactured by AstraZeneca.
The generic name is capivasertib.
The brand name is Truqap.
Capivasertib is manufactured in regulated pharmaceutical facilities under AstraZeneca’s global manufacturing network, supplying the USA, EU, and UK markets.
Adults with HR-positive, HER2-negative advanced breast cancer with one or more PIK3CA, AKT1 or PTEN alterations, after progression on endocrine therapy, used with fulvestrant.
400 mg twice daily for 4 days, followed by 3 days off, in each week.
No. It is patented and marketed by AstraZeneca as Truqap. Outside registered markets it is available only through authorised or named-patient routes.
Truqap (Capivasertib) is developed and sold by AstraZeneca. PharmaTradz handles enquiries for authorised supply of the originator product, named-patient import where it is not registered, and licensing or development work ahead of patent expiry.
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