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Capivasertib bulk supplier for pharma manufacturers

Capivasertib 160 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 160 mg

Reference Brands: Truqap (USA)

Category: Oncology Cancer Care

Capivasertib 160 mg tablets are an AKT inhibitor used with fulvestrant for hormone receptor-positive, HER2-negative advanced breast cancer with PIK3CA, AKT1 or PTEN changes. It is taken twice daily, four days on and three days off. It is made by AstraZeneca as Truqap and is a patented innovator product. Supply is through authorised distribution or named-patient import; ask us which route fits your country.

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Product Description:

Capivasertib, also known by the brand name Truqap, is an oral targeted anticancer therapy used in combination with fulvestrant for the treatment of adults with hormone receptor-positive, HER2-negative advanced or metastatic breast cancer. It is specifically indicated for patients whose disease has progressed during or after prior hormone therapy and who have genetic alterations in the PIK3CA, AKT1, or PTEN genes.

Capivasertib works by selectively inhibiting AKT, a key protein involved in cell signaling pathways that regulate cancer cell growth, survival, and metabolism. By blocking AKT activity, capivasertib disrupts these pathways, helping to slow tumor growth and potentially induce cancer cell death. It belongs to the class of kinase inhibitors and represents an important advancement in precision oncology.

The drug is administered orally under specialist supervision and is being actively studied for use in other cancer types where AKT pathway abnormalities play a role. Capivasertib’s targeted mechanism allows for a more personalized treatment approach, offering improved outcomes for patients with specific molecular profiles while supporting long-term disease control in advanced breast cancer.

How Capivasertib is supplied today, and licensing ahead of patent expiry

Named-patient import Where a patient needs the product in a market where it is not registered, named-patient import is the lawful route. It requires the treating physician's documentation and authorisation from the destination regulator. We handle this pathway. Named-patient access
Authorised distribution For registered markets, supply runs through the manufacturer's authorised distribution channel. We can identify the authorised route for your market and tell you whether the product is registered there at all. Innovator sourcing
A genericised alternative Where the clinical requirement is the drug class rather than this specific molecule, there is often an off-patent alternative that is faster to register and materially cheaper. Tell us the indication and target market and we will say plainly whether one exists. Discuss alternatives
Licensing and generic development Patents expire country by country, and in many countries development and dossier filing can start before expiry under research and regulatory-review exemptions. We connect manufacturers developing this molecule, dossier holders, licensees and tech-transfer partners for markets where it is, or will become, off-patent. Partner on this molecule
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Frequently Asked Questions

Capivasertib is used in combination with endocrine therapy to treat adults with hormone receptor-positive, HER2-negative advanced or metastatic breast cancer that has specific AKT pathway alterations.

Capivasertib is a small-molecule synthetic AKT inhibitor designed to block intracellular signaling pathways involved in cancer cell growth and survival.

The trade name is Truqap.

Capivasertib (Truqap) is manufactured by AstraZeneca.

The generic name is capivasertib.

The brand name is Truqap.

Capivasertib is manufactured in regulated pharmaceutical facilities under AstraZeneca’s global manufacturing network, supplying the USA, EU, and UK markets.

Adults with HR-positive, HER2-negative advanced breast cancer with one or more PIK3CA, AKT1 or PTEN alterations, after progression on endocrine therapy, used with fulvestrant.

400 mg twice daily for 4 days, followed by 3 days off, in each week.

No. It is patented and marketed by AstraZeneca as Truqap. Outside registered markets it is available only through authorised or named-patient routes.

Truqap (Capivasertib) is developed and sold by AstraZeneca. PharmaTradz handles enquiries for authorised supply of the originator product, named-patient import where it is not registered, and licensing or development work ahead of patent expiry.

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