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Methotrexate bulk supplier for pharma manufacturers

Methotrexate Suppliers & Bulk Manufacturers

Available Forms: Oral tablets, Injection (IV and IM)

Available Strengths: Tablets: 2.5 mg, 5 mg, 10 mg, 15 mg; IV/IM: 25 mg/mL

Reference Brands: Trexall®, Rheumatrex® (EU & US)

Category: Oncology Cancer Care

Methotrexate (brands Trexall®, Rheumatrex®) is a chemotherapy drug used to treat leukemia, lymphoma, breast cancer, and osteosarcoma. Available in oral tablets (2.5 mg to 15 mg) and injectable forms (25 mg/mL), Methotrexate is sourced by B2B pharma suppliers in the US and EU. It is GMP-compliant and widely used for both oncology treatments and autoimmune conditions, ensuring reliable supply and competitive pricing for hospitals and oncology centers.

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Product Description: Methotrexate, marketed under brand names like Trexall® and Rheumatrex®, is an essential chemotherapy drug and immunosuppressant used in the treatment of various oncologic conditions such as leukemia, lymphoma, breast cancer, and osteosarcoma. Available in oral and injectable forms, with strengths ranging from 2.5 mg to 25 mg/mL, Methotrexate is sourced globally by B2B pharmaceutical suppliers. It is GMP-compliant, ensuring consistent quality for hospitals and oncology centers. Methotrexate's wide availability in the US and EU supports effective cancer care at competitive pricing, making it a trusted option for treating aggressive cancers and autoimmune disorders.

Methotrexate — third party manufacturing & bulk supply

Methotrexate is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Methotrexate is supplied as Oral tablets, Injection (IV and IM) — supplied in more than one dosage form, each with its own manufacturing economics, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Methotrexate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Methotrexate is listed as Oral tablets, Injection (IV and IM) in Tablets: 2.5 mg, 5 mg, 10 mg, 15 mg; IV/IM: 25 mg/mL. Further strengths and pack presentations are confirmed with the manufacturer at RFQ stage.

Methotrexate is referenced against Trexall®, Rheumatrex® (EU & US). Reference brands are shown for identification only and remain the property of their respective trademark owners.

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