Cabazitaxel bulk supplier for pharma manufacturers

Cabazitaxel 60 mg/1.5 mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 60 mg/1.5 mL

Reference Brands: Jevtana (US/EU)

Cabazitaxel is used in the treatment of advanced prostate cancer. It is used to treat cancer of the prostate gland that has not responded to treatment with other anticancer medicines. It may be used alone or in combination with steroid medicines.

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Product Description:

Cabazitaxel is a semi-synthetic taxane that stabilises microtubules, preventing the dynamic assembly and disassembly that mitosis requires. Its design point is resistance: it has poor affinity for P-glycoprotein, the efflux pump that tumours use to expel docetaxel and paclitaxel, so it retains activity in tumours that have become taxane-resistant.

It is used with prednisone for metastatic castration-resistant prostate cancer previously treated with a docetaxel-containing regimen, where it demonstrated a survival benefit — the first agent to do so in that setting. Severe neutropenia is the dominant toxicity and the reason for the boxed warning; primary prophylaxis with growth factor is recommended in patients at higher risk, and deaths from neutropenic sepsis occurred in trials. Hypersensitivity reactions require premedication with antihistamine, corticosteroid and H2 blocker. Diarrhoea can be severe. It is contraindicated in significant hepatic impairment.

Sourcing notes. Patent position varies by market and generics exist in some. It is supplied as a concentrate requiring two-step dilution — a preparation sequence that has caused dosing errors, so pharmacy familiarity matters. Cytotoxic containment and closed-system transfer apply.

Cabazitaxel — third party manufacturing & bulk supply

Cabazitaxel 60 mg/1.5 mL is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Cabazitaxel is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Cabazitaxel listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Cabazitaxel is listed as Injection in 60 mg/1.5 mL. Further strengths and pack presentations are confirmed with the manufacturer at RFQ stage.

Cabazitaxel is referenced against Jevtana (US/EU). Reference brands are shown for identification only and remain the property of their respective trademark owners.