Ziconotide Acetate 25 mcg/mL Suppliers & Bulk Manufacturers

Available Forms: Intrathecal solution

Available Strengths: 25 mcg/mL

Reference Brands: Prialt (USA/EU)

Category: Pain Management

Ziconotide Acetate is a Pain Management product available as Intrathecal solution in strengths 25 mcg/mL. It corresponds to the reference brand Prialt (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Ziconotide, marketed under the brand name Prialt, is an atypical analgesic agent used for the management of severe and chronic pain. It is a synthetic form of an ω-conotoxin peptide derived from the venom of the cone snail (Conus magus). Unlike conventional analgesics, ziconotide is administered intrathecally, directly into the spinal fluid, due to poor efficacy and significant side effects when delivered orally or intravenously.

Intrathecal administration allows ziconotide to selectively block N-type voltage-sensitive calcium channels in the central nervous system, inhibiting the transmission of pain signals without the addictive potential associated with opioids. Because of its invasive delivery method and high cost, ziconotide therapy is generally reserved for patients who are intolerant of or refractory to other treatments, including systemic analgesics, adjunctive therapies, or intrathecal morphine.

Ziconotide’s unique mechanism of action and targeted efficacy make it a valuable option in specialized pain management, especially in cases where conventional therapies fail. Ongoing research aims to explore alternative formulations that could allow less invasive administration while maintaining the drug’s potent analgesic effects. Prialt remains an important treatment for patients requiring intrathecal therapy to manage severe chronic pain.