Sparsentan 200mg, 400mg Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 200mg, 400mg
Reference Brands: Filspari (USA)
Category: Nephrology
Sparsentan is an oral dual endothelin type A receptor (ET_A) and angiotensin II type 1 receptor (AT_1) antagonist, designed to reduce proteinuria in adults with primary immunoglobulin A nephropathy (IgAN) who are at risk of rapid disease progression. It is marketed under the brand name Filspari and available in 200 mg and 400 mg tablets. Because of its novel mechanism and risk profile (including hepatotoxicity), it is subject to a restricted drug-distribution program.
Sparsentan — third party manufacturing & bulk supply
Sparsentan 200mg, 400mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Sparsentan listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Sparsentan →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Sparsentan is used to treat rare kidney diseases such as IgA nephropathy and focal segmental glomerulosclerosis (FSGS). It helps reduce proteinuria (excess protein in the urine) and slows the progression of kidney damage. Sparsentan works by blocking two key pathways involved in kidney injury — endothelin type A and angiotensin II type 1 receptors — offering dual protection to the kidneys.
Sparsentan is made from the active ingredient sparsentan, a dual-acting angiotensin II and endothelin receptor antagonist. Its chemical name is (2E)-3-[2-butyl-1-[(4′-carboxy[1,1′-biphenyl]-4-yl)methyl]-7-(2-methylpropyl)-2,6-dioxo-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-yl]-N-(2-hydroxy-2-phenylethyl)acrylamide. It is formulated with excipients such as lactose monohydrate, cellulose, and magnesium stearate depending on the dosage form.
The trade name of sparsentan is Filspári in the United States and Kinpeygo in the European Union.
Sparsentan (Filspári/Kinpeygo) is developed and marketed by Travere Therapeutics in the United States and by CSL Vifor in Europe under a licensing agreement.
The generic name of the drug is sparsentan.
The brand names of sparsentan are Filspári (USA) and Kinpeygo (EU).
Sparsentan is manufactured in the United States by Travere Therapeutics and in Europe by CSL Vifor, with global distribution to markets where treatment for IgA nephropathy and FSGS is approved.
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