Rifapentine 150 mg, 300 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 150 mg, 300 mg

Reference Brands: Priftin (USA)

Category: Antibiotics

Rifapentine is a Antibiotics product available as Tablets in strengths 150 mg, 300 mg. It corresponds to the reference brand Priftin (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Rifapentine, marketed under the brand name Priftin, is an antibiotic used for the treatment and prevention of tuberculosis (TB). It belongs to the rifamycin class and works by inhibiting bacterial DNA-dependent RNA polymerase, effectively suppressing the replication of Mycobacterium tuberculosis. Rifapentine is administered orally and is used in combination with other antituberculosis medications for active TB, while in latent TB infection, it is typically combined with isoniazid.

Rifapentine’s long half-life allows for less frequent dosing, improving patient adherence and overall treatment outcomes. Clinical studies have shown that a weekly, directly observed regimen of rifapentine with isoniazid for three months is as effective as a daily, self-administered regimen of isoniazid for nine months in preventing active TB in HIV-negative individuals with latent TB. This shorter regimen also demonstrated higher treatment completion rates and lower hepatotoxicity, although the incidence of treatment-limiting adverse events was slightly higher.

Rifapentine’s efficacy, safety profile, and convenient dosing schedule make it an important option for TB management, particularly for patients requiring combination therapy or those at risk of poor adherence to longer regimens. Priftin continues to play a critical role in both latent and active TB treatment strategies worldwide.