Pretomanid 200 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 200 mg

Reference Brands: Afiniti

Category: Antibiotics

Pretomanid is a Antibiotics product available as Tablets in strengths 200 mg. It corresponds to the reference brand Afiniti. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Pretomanid is an antibiotic medication used in the treatment of multi-drug-resistant tuberculosis (MDR-TB) affecting the lungs. It is specifically indicated for use in adults as part of combination therapy with bedaquiline and linezolid for pulmonary extensively drug-resistant tuberculosis, or in patients who are treatment-intolerant or nonresponsive to standard MDR-TB regimens.

As a nitroimidazooxazine antimycobacterial agent, pretomanid works by inhibiting the synthesis of mycobacterial cell wall components and generating reactive nitrogen species that kill Mycobacterium tuberculosis. Its targeted mechanism makes it highly effective against drug-resistant strains of TB, which are difficult to treat with conventional antibiotics.

Pretomanid is administered orally as 200 mg tablets, allowing convenient integration into combination therapy regimens. When used alongside bedaquiline and linezolid, pretomanid has shown significant clinical efficacy in improving treatment outcomes in adults with highly resistant pulmonary tuberculosis.

This therapy represents an important advancement in global TB management, providing a viable option for patients with limited treatment choices and helping to combat the growing challenge of drug-resistant tuberculosis worldwide.