Poliomyelitis Vaccine Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: -

Reference Brands:

Category: Vaccines

Injection is a poliomyelitis vaccine. Vaccines are used to protect you or your children against infectious diseases. This vaccine is used to prevent poliomyelitis in infants, children, and adults. Poliomyelitis (also known as polio) is an infectious disease caused by polio virus. People can get this infection from drinking water or eating food with polio in it, or it can be spread from person to person. It can infect a person’s spinal cord, brain and cause paralysis (cannot move parts of the body).

Product Description:

Polio vaccine exists in two quite different forms, and which one a programme uses is a strategic decision, not a preference. Inactivated poliovirus vaccine, given by injection, contains killed virus: it produces excellent blood antibody that prevents paralytic disease, cannot revert to a virulent form, and is safe in immunodeficiency, but it induces less gut immunity. Oral poliovirus vaccine contains live attenuated virus: it produces strong intestinal immunity that interrupts transmission, spreads to unvaccinated contacts, and costs very little — but it can, rarely, revert and cause vaccine-derived paralytic polio.

Eradication strategy has shifted accordingly: countries free of the disease use inactivated vaccine, while outbreak response uses oral vaccine for its transmission-blocking effect, increasingly in a novel formulation engineered to be genetically more stable. Wild poliovirus now circulates in very few countries, and most remaining paralysis worldwide is vaccine-derived.

Sourcing notes. An enquiry must state inactivated or oral, and for oral which serotypes are included — the formulations differ. Oral vaccine is supplied with a vaccine vial monitor and can tolerate a brief break in cold chain; inactivated vaccine cannot and must never be frozen. Supply is dominated by UNICEF tender and WHO prequalification.