Phenylephrine Chlorpheniramine Suppliers & Bulk Manufacturers

Available Forms: Syrup

Available Strengths: Phenylephrine(2.5 mg) + Chlorpheniramine(1 mg)per 5 mL

Reference Brands: -

Category: Allergy Medication

Phenylephrine 2.5 mg and chlorpheniramine 1 mg per 5 mL syrup, a liquid decongestant and antihistamine for cold and allergy symptoms in children. For pharmacy wholesalers, distributors and importers.

Product Description:

This syrup combines phenylephrine 2.5 mg, a sympathomimetic decongestant that narrows swollen nasal blood vessels, with chlorpheniramine maleate 1 mg, a first-generation H1 antihistamine, in each 5 mL. The low per-dose strength and liquid form exist for children who cannot swallow tablets and whose dose is measured in millilitres. Products differ in sweetener, flavour, alcohol and preservative system, and paediatric markets increasingly expect sugar-free, alcohol-free versions with a measuring device in the pack.

It relieves runny and blocked nose, sneezing and watery eyes in colds and allergic rhinitis. Age limits matter: US labelling advises against cough and cold products under four, and UK guidance sets the threshold at six, so check your regulator's age floor. Chlorpheniramine causes drowsiness and, in some children, excitability. Phenylephrine must not be combined with MAO inhibitors or used within 14 days of stopping one. A US FDA advisory panel judged oral phenylephrine ineffective as a decongestant, so its status may change.

Sourcing notes. Bottles are usually amber PET or glass with a child-resistant cap, plus a dosing cup or oral syringe graduated in millilitres; confirm which is supplied. Ask for a CoA per batch with assay of both actives, preservative content, pH and microbial limits, and for in-use stability data after opening. Liquids for hot humid markets need zone IVb data; no cold chain is required. Request the GMP certificate, a CoPP and a CTD or ACTD dossier. State bottle volume, flavour, sugar-free requirement and label language.