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Perflutren bulk supplier for pharma manufacturers

Perflutren 0.19 mg/ ml Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 0.19 mg/ ml

Reference Brands: Definity (USA), Optison (USA), Luminity (EU)

Category: Contrast Agent

Perflutren is a Contrast Agent product available as Injection in strengths 0.19 mg/ ml. It corresponds to the reference brands Definity (USA), Optison (USA), Luminity (EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Perflutren lipid microspheres are supplied as a sterile injectable suspension designed for use as a contrast agent in diagnostic ultrasound imaging. The formulation consists of liposome-encapsulated microspheres containing the fluorocarbon gas perflutren. These microspheres are administered intravenously to enhance ultrasound image quality during clinical procedures, particularly in cardiovascular imaging.

Perflutren lipid microspheres work by exploiting the difference in acoustic impedance between the perflutren gas and surrounding blood. Because the acoustic impedance of the microspheres is significantly lower than that of blood, incoming ultrasound waves are strongly scattered and reflected at the microsphere–blood interface. This interaction produces a marked increase in echogenicity, allowing clearer visualization of blood flow, cardiac chambers, and endocardial borders.

The enhanced contrast provided by perflutren lipid microspheres improves diagnostic accuracy in patients with suboptimal baseline ultrasound images. The microspheres remain within the vascular space and are rapidly eliminated after imaging, with the perflutren gas exhaled through the lungs. This targeted, transient contrast effect makes perflutren lipid microspheres a valuable tool for real-time ultrasound contrast enhancement in routine clinical practice.

Perflutren — third party manufacturing & bulk supply

Perflutren 0.19 mg/ ml is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Perflutren listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions


Perflutren is used as an ultrasound contrast agent to enhance the quality of echocardiographic imaging. It helps improve visualization of cardiac chambers, endocardial borders, and blood flow, particularly in patients with suboptimal baseline ultrasound images.


Perflutren is an inert, fluorinated hydrocarbon gas. In clinical use, it is formulated into microspheres with either a lipid or protein shell to allow intravenous administration during diagnostic ultrasound procedures.


Common trade names include Definity, Optison, and Luminity, depending on the formulation and region.


Perflutren-based contrast agents are manufactured by companies such as Lantheus Medical Imaging and GE Healthcare, depending on the specific brand.


The generic name of the drug is perflutren.


Brand names include Definity, Optison, and Luminity.


Perflutren-based products are manufactured under the specifications of their respective marketing authorization holders in compliance with international pharmaceutical and medical imaging regulations.

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