Oxacillin Sodium 300 mg, 250 mg, 500 mg, 1 g Suppliers & Bulk Manufacturers

Available Forms: Capsule / Injection

Available Strengths: 300 mg, 250 mg, 500 mg, 1 g

Reference Brands: Bactocill (USA/EU)

Category: Antibiotics

Oxacillin Sodium is a Antibiotics product available as Capsule / Injection in strengths 300 mg, 250 mg, 500 mg, 1 g. It corresponds to the reference brand Bactocill (USA/EU). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Oxacillin is a semisynthetic, penicillinase-resistant β-lactam antibiotic that is closely related to methicillin and has largely replaced it in clinical practice. It is part of a class of antibiotics that includes nafcillin, cloxacillin, dicloxacillin, and flucloxacillin. Oxacillin is specifically designed to resist degradation by penicillinase enzymes produced by bacteria such as Staphylococcus aureus, making it highly effective for treating infections caused by penicillin-resistant strains of this bacterium.

Clinically, oxacillin is widely used in the United States to treat serious staphylococcal infections, including skin and soft tissue infections, bone and joint infections, endocarditis, and sepsis. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. However, the extensive use of oxacillin has contributed to the emergence of methicillin-resistant and oxacillin-resistant Staphylococcus aureus (MRSA/ORSA), which are increasingly prevalent worldwide. These resistant strains require alternative treatments, such as vancomycin or newer antibiotics, to effectively manage infections. Oxacillin remains a cornerstone therapy for penicillinase-producing staphylococcal infections when the bacteria are susceptible, offering reliable efficacy and a well-established safety profile.