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Nafarelin Acetate bulk supplier for pharma manufacturers

Nafarelin Acetate 2 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Nasal Spray

Available Strengths: 2 mg/mL

Reference Brands: Synarel (USA)

Category: Women's Health

Nafarelin acetate nasal spray (2 mg/ml) is a GnRH agonist used for endometriosis and in IVF to control ovulation; in some countries it is also used for early puberty in children. The reference brand is Synarel. Ask PharmaTradz for a quote; we confirm the manufacturer, registration documents and lead time for your country.

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Product Description:

Nafarelin is a synthetic gonadotropin-releasing hormone (GnRH) agonist used in the management of hormone-dependent conditions. It is primarily indicated for the treatment of endometriosis and central precocious puberty, and is also used in selected cases for uterine fibroids and hormone regulation protocols. By continuously stimulating GnRH receptors in the pituitary gland, nafarelin initially increases luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release, followed by receptor down-regulation and suppression of sex hormone production. This results in reduced estrogen or testosterone levels, depending on the treatment context.

Through its hormone-suppressing action, nafarelin helps control symptoms driven by excess sex hormones, such as endometrial tissue growth and early pubertal changes. It is also used in controlled ovarian stimulation programs for in vitro fertilization (IVF) and in certain gender-affirming hormone therapy protocols to suppress endogenous hormone production. Nafarelin is marketed under brand names such as Synarel and is prescribed under specialist supervision, with treatment duration and dosing tailored to the specific indication and patient response.

Nafarelin Acetate — third party manufacturing & bulk supply

Nafarelin Acetate 2 mg/mL is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Nafarelin Acetate is supplied as Nasal Spray — a dosage form priced by order value, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Nafarelin Acetate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Nafarelin acetate is used for the treatment of endometriosis and central precocious puberty by suppressing sex hormone production.

It is a synthetic gonadotropin-releasing hormone (GnRH) agonist peptide formulated as the acetate salt for intranasal administration.

The trade name is Synarel.

It has been marketed by Pfizer and its related divisions in approved markets.

The generic name is nafarelin acetate.

The brand name is Synarel.

How is nafarelin used for endometriosis?

One spray (200 micrograms) into one nostril in the morning and the other nostril in the evening, usually for 6 months.

Menopause-like symptoms such as hot flushes and vaginal dryness, and loss of bone density with long use.

Synarel (Pfizer) is the main product and supply is limited in many countries, so we confirm sources before quoting.

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