Lodoxamide 0.1%w/v Suppliers & Bulk Manufacturers

Available Forms: Eye Drops

Available Strengths: 0.1%w/v

Reference Brands: Alomide (USA), Lomide (EU)

Category: Opthalmology

Lodoxamide tromethamine is an ophthalmic mast cell stabilizer used to prevent and treat allergic conjunctivitis, including vernal conjunctivitis. It works by inhibiting the release of histamine and other mediators from mast cells, reducing itching, redness, and inflammation in the eyes. Typically, it is administered as 0.1% eye drops, 1–2 drops in each eye four times daily. It is often prescribed for patients with chronic or seasonal allergic eye conditions.

Product Description:

Lodoxamide is a mast cell stabiliser. It prevents mast cells from degranulating when allergen binds their surface IgE, so histamine and other mediators are never released. It has no antihistamine action of its own, which means it does not relieve an attack already under way — it prevents the next one. Effect builds over days to weeks of regular use.

It is used for the more serious allergic eye diseases rather than ordinary hay fever conjunctivitis: vernal keratoconjunctivitis, vernal conjunctivitis and vernal keratitis, conditions that can threaten the cornea in children and young adults, often seasonally and in hot climates. Regular use through the season is what makes it work, and patients must understand that stopping when symptoms settle allows them to return. Transient burning or stinging on instillation is the common complaint. Contact lenses should not be worn during treatment of active allergic eye disease.

Sourcing notes. Off patent. Demand is strongly seasonal and geographically concentrated in hot, dry regions where vernal disease is common — a different market from routine allergy drops, and one where public hospital and programme purchasing dominates. Supplied as a preserved multi-dose solution.