Doxecitine + Doxribtimine 2g+2g Suppliers & Bulk Manufacturers
Available Forms: Oral Solution
Available Strengths: 2g+2g
Reference Brands: Kygevvi (USA)
Category: Orphan Drugs
Doxecitine (2′‑deoxycytidine) and doxribtimine (2′‑deoxythymidine) provide nucleosides to restore mitochondrial DNA synthesis in patients with TK2 deficiency. This helps improve mitochondrial function in muscle cells, reduce muscle weakness, delay disease progression, and improve survival.
Doxecitine + Doxribtimine — third party manufacturing & bulk supply
Doxecitine + Doxribtimine 2g+2g is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
What to include when you enquire
- Destination market — determines which manufacturers hold the right site-level approvals
- First order quantity and estimated annual volume
- Whether you need a registration dossier or the product is already registered
- Packaging, labelling and language requirements
- Incoterms and required shelf life
Manufacturers of Doxecitine + Doxribtimine listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.
Request a quote for Doxecitine + Doxribtimine →The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
This combination is used to treat Thymidine Kinase 2 Deficiency (TK2d), a rare, inherited mitochondrial disorder that leads to progressive muscle weakness, breathing problems, and mitochondrial DNA depletion. It is the first and currently only approved therapy targeting the underlying cause of TK2d, aiming to restore mitochondrial DNA replication and improve cell energy metabolism.
Doxecitine is a pyrimidine nucleoside — chemically deoxycytidine — and Doxribtimine is deoxythymidine (thymidine nucleoside). Together they supply deoxynucleosides needed for mitochondrial DNA synthesis. The formulation also contains inactive excipients that permit the preparation of an oral solution.
The trade name for this combination is Kygevvi.
Kygevvi is manufactured by UCB, Inc..
The generic names are doxecitine and doxribtimine.
The brand name is Kygevvi.
Kygevvi is produced by UCB, Inc. in regulated pharmaceutical manufacturing facilities and supplied under globally approved Good Manufacturing Practice (GMP) standards.
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