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Diphenhydramine Hydrochloride bulk supplier for pharma manufacturers

Diphenhydramine Hydrochloride Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 50 mg/mL in 1 mL or 2 mL vials

Reference Brands: Benadryl®

Category: Allergy Medication

Diphenhydramine HCl Injection (50 mg/mL) is a fast-acting antihistamine used for severe allergic reactions, anaphylaxis support, and motion sickness. Available in 1 mL/2 mL vials, marketed as Benadryl® and generics in the US and EU.

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📘 Sourcing Guide

Product Description:

Diphenhydramine Hydrochloride Injection is a fast-acting first-generation antihistamine, widely used for acute allergic reactions, anaphylaxis adjunct, and drug-induced extrapyramidal symptoms. Commonly supplied as 50 mg/mL in 1 mL or 2 mL vials, it is administered via IM or slow IV injection. Marketed in the US under brands like Benadryl® Injection, and widely available as generics in both the EU and US. Manufactured in GMP-certified facilities, this injection is ideal for hospital supply, emergency kits, and B2B distribution.

Diphenhydramine Hydrochloride — third party manufacturing & bulk supply

Diphenhydramine Hydrochloride is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Diphenhydramine Hydrochloride listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Diphenhydramine Hydrochloride is used to relieve symptoms of allergy, hay fever, and the common cold, such as runny nose, sneezing, itching, and watery eyes. It is also used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness, and to help with short-term sleep problems.

Diphenhydramine Hydrochloride is made from an ethanolamine derivative that acts as a first-generation antihistamine by blocking histamine H1 receptors in the body.

Common trade names of Diphenhydramine Hydrochloride include Benadryl, Nytol, and Unisom.

Diphenhydramine Hydrochloride is made by Johnson & Johnson (Benadryl), McNeil Consumer Healthcare, and other generic pharmaceutical manufacturers.

The generic name of the product is Diphenhydramine Hydrochloride.

The brand names of Diphenhydramine Hydrochloride are Benadryl, Nytol, and Unisom.

Diphenhydramine Hydrochloride is manufactured by several pharmaceutical companies in the United States, the United Kingdom, and India.

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