Diethylpropion Hydrochloride 25mg, 75mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 25mg, 75mg

Reference Brands: Tenuate (USA)

Category: Weight Loss drugs

Diethylpropion is a sympathomimetic amine used as a short-term adjunct in weight reduction for obese patients. It acts as an appetite suppressant by stimulating the central nervous system, increasing energy expenditure, and reducing hunger sensations.

Product Description:

Diethylpropion, also known as amfepramone, is a sympathomimetic amine that suppresses appetite by increasing noradrenaline release in the hypothalamic centres governing satiety. It is structurally related to amphetamine but has notably less effect on dopamine, which gives it a milder stimulant profile and lower abuse potential than others in the class — though not an absent one.

It is licensed for short-term use, typically up to twelve weeks, as an adjunct to diet, exercise and behavioural modification in obesity. Weight lost is modest and tends to return when treatment stops, which is the central difficulty with the whole class. Dry mouth, insomnia, irritability, palpitations and raised blood pressure are common. Primary pulmonary hypertension and valvular heart disease have been associated with prolonged use of appetite suppressants, which is what ended the era of long-term anorectic prescribing.

Sourcing notes. A Schedule IV controlled substance in the United States. European regulators reviewed this class and recommended withdrawal of marketing authorisations, so availability across the EU is restricted or absent — confirm the destination's current position before quoting. Import licences and quota apply. Two strengths, immediate and controlled release, are not interchangeable.