Cimetidine Injection 200 mg and 300 mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 200 mg and 300 mg

Reference Brands: Tagamet(US & EU)

Category: Gastrointestinal Drugs

Cimetidine injection, 200 mg and 300 mg in ampoules or vials, the parenteral H2-receptor antagonist for hospital acid suppression. For hospital buyers, tender agencies, importers and distributors of sterile injectables.

Product Description:

Cimetidine injection is the parenteral form of the H2-receptor antagonist, for patients who cannot take tablets or who need acid suppression in hospital. Blocking H2 receptors on parietal cells reduces gastric acid output and volume. This page covers 200 mg and 300 mg presentations, typically clear solutions such as 200 mg or 300 mg in 2 mL. It can be given by slow intravenous injection, by intravenous infusion or intramuscularly, which gives ward and theatre staff flexibility.

Hospital uses have included ulcers and hypersecretory states in patients unable to swallow, stress ulcer prophylaxis in critical care, and reducing stomach acidity before anaesthesia where aspiration is a concern. A bolus must run over at least five minutes, because rapid injection has been linked with bradycardia, arrhythmia and hypotension. Patients switch to oral therapy when practical, and doses are adjusted in renal impairment. Like the tablets, the injection inhibits hepatic cytochrome P450 enzymes, which matters with phenytoin, theophylline, lidocaine or warfarin.

Sourcing notes. The injection is prescription-only and mainly a hospital product. Fewer markets keep it registered than in the past, so confirm current status with your regulator before tendering. Ask for a CTD or ACTD dossier with sterility assurance, sterilisation method, bacterial endotoxin and particulate results, and compatibility data with common infusion fluids. Type I glass ampoules or vials are standard, stored as labelled. Request a CoA per batch, a GMP certificate for sterile manufacture and a CoPP. State strength per container, ampoule or vial format, quantity and label language.