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Agomelatine bulk supplier for pharma manufacturers

Agomelatine Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 25 mg, 50 mg

Reference Brands: Valdoxan (EU/UK), Thymanax (India/ Middle East)

Category: Psychiatry / Mental Health

Agomelatine is available in Tablets and strengths such as 25 mg, 50 mg. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Agomelatine is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Agomelatine can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Agomelatine is a novel antidepressant with a unique mechanism of action, functioning as a melatonergic agonist and a 5-HT2C antagonist. This dual activity helps regulate the sleep-wake cycle and improves mood by promoting the release of norepinephrine and dopamine in the brain. It is primarily used to treat major depressive disorder (MDD) in adults, offering benefits for both psychiatric and primary care patients who have not achieved full remission with conventional antidepressants.

One of the distinguishing features of agomelatine is its favorable side-effect profile. It is generally well-tolerated, with minimal risk of sexual dysfunction, weight gain, or discontinuation syndrome, and it is relatively safe in cases of overdose. However, a small percentage of patients may experience elevated liver enzymes, which requires monitoring during treatment. Agomelatine’s ability to improve sleep patterns while alleviating depressive symptoms makes it a promising option for patients struggling with persistent depression. With further clinical evaluation, it may become a valuable addition to the available pharmacological strategies for managing depression in diverse healthcare settings.

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Frequently Asked Questions

Agomelatine is used to treat major depressive disorder (MDD) in adults. It helps improve mood, reduce symptoms of depression such as sadness and loss of interest, and restore normal sleep patterns by regulating the circadian rhythm.

Agomelatine is a synthetic pharmaceutical compound that acts as a melatonergic antidepressant. It functions as an agonist at melatonin MT1 and MT2 receptors and as an antagonist at serotonin 5-HT2C receptors to balance neurotransmitters and improve depressive symptoms.

Agomelatine is marketed under the brand name Valdoxan in Europe and several other countries, and as Thymanax in some emerging markets.

Agomelatine (Valdoxan) is manufactured and marketed by Servier Laboratories in Europe and distributed in other regions through authorized partners.

The generic name is Agomelatine.

The most recognized brand name is Valdoxan.

Agomelatine is manufactured in regulated pharmaceutical facilities that comply with international quality and safety standards, primarily in Europe, with distribution to other approved markets.

Yes, Agomelatine is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Agomelatine is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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