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Vadadustat bulk supplier for pharma manufacturers

Vadadustat 150 mg, 300 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 150 mg, 300 mg

Reference Brands: Vafseo (EU/EU/UK)

Category: Anemia

Vadadustat is a Anemia product available as Tablets in strengths 150 mg, 300 mg. It corresponds to the reference brand Vafseo (EU/EU/UK). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

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📘 Sourcing Guide

Product Description:

Vadadustat is an oral medication used for the treatment of symptomatic anemia associated with chronic kidney disease (CKD), particularly in adult patients who are on dialysis. Anemia is a common complication in CKD due to reduced production of erythropoietin, a hormone responsible for stimulating red blood cell formation. Vadadustat works by inhibiting hypoxia-inducible factor prolyl hydroxylase (HIF-PH) enzymes, which helps stabilize hypoxia-inducible factors in the body. This process stimulates the natural production of erythropoietin, improves iron metabolism, and supports the formation of red blood cells.

By targeting the body’s natural response to low oxygen levels, vadadustat offers a different mechanism compared to traditional erythropoiesis-stimulating agents (ESAs). The medicine is administered orally in tablet form, making it a convenient treatment option for patients requiring long-term anemia management due to kidney disease. Vadadustat is marketed under the brand name Vafseo in several regulated pharmaceutical markets. It has been developed to help maintain hemoglobin levels within a target range and reduce the need for blood transfusions in eligible patients. The drug is typically prescribed and monitored by healthcare professionals experienced in managing anemia in chronic kidney disease patients.

Vadadustat — third party manufacturing & bulk supply

Vadadustat 150 mg, 300 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Vadadustat listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Vadadustat is used to treat anemia caused by chronic kidney disease (CKD), especially in adult patients who are on dialysis. It works by stimulating the body’s natural response to low oxygen levels, which increases the production of erythropoietin and helps the body produce more red blood cells.

Vadadustat is a synthetic small-molecule drug that inhibits hypoxia-inducible factor prolyl hydroxylase enzymes. By blocking these enzymes, it stabilizes hypoxia-inducible factors (HIF), which help regulate genes involved in red blood cell production and iron metabolism.

The main trade name of vadadustat in international markets is Vafseo.

Vadadustat was developed by Akebia Therapeutics and is marketed in different regions through partnerships with pharmaceutical companies responsible for commercialization and distribution in approved markets.

The generic name of Vafseo is vadadustat.

The brand name of vadadustat is Vafseo.

Vadadustat finished formulations are manufactured by licensed pharmaceutical manufacturers working with Akebia Therapeutics and its regional partners in approved regulatory markets such as the United States, Europe, and Japan.

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