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Topiramate bulk supplier for pharma manufacturers

Topiramate Suppliers & Bulk Manufacturers

Available Forms: Tablet / Capsule / Oral solution

Available Strengths: 25 mg, 50 mg, 100 mg, 200 mg, 25 mg/5 mL

Reference Brands: Topamax (USA/EU), Trokendi XR (USA)

Category: Neurology

Topiramate is available in Tablet / Capsule / Oral solution and strengths such as 25 mg, 50 mg, 100 mg, 200 mg, 25 mg/5 mL. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Topiramate is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Topiramate can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Topiramate, marketed under the brand name Topamax and other brand names, is an orally administered medication primarily used for the management of epilepsy and the prevention of migraine headaches. In epilepsy, topiramate is indicated for the treatment of generalized tonic-clonic seizures as well as partial-onset or focal seizures, helping to reduce seizure frequency and improve overall seizure control. Its broad-spectrum antiepileptic activity makes it suitable for use in both adult and pediatric patients.

Topiramate works through multiple mechanisms, including modulation of voltage-gated sodium channels, enhancement of gamma-aminobutyric acid (GABA) activity, inhibition of excitatory glutamate receptors, and weak inhibition of carbonic anhydrase enzymes. This multi-targeted approach contributes to its effectiveness in controlling abnormal neuronal activity and preventing migraine attacks.

In addition to its approved uses, topiramate has been employed off-label for conditions such as alcohol dependence and essential tremor, demonstrating its versatility in neurological and behavioral disorders. Its oral formulation allows for convenient administration, and dosage can be adjusted according to patient needs and tolerability. Topiramate is considered a valuable option for long-term management of seizures and migraine prevention, providing sustained therapeutic benefit with careful monitoring.

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Frequently Asked Questions

Topiramate is used for the treatment of epilepsy, including partial-onset and generalized tonic-clonic seizures, and for the prevention of migraine headaches in adults and adolescents.

Topiramate is a synthetic sulfamate-substituted monosaccharide compound designed to act on multiple neuronal pathways involved in seizure activity and migraine pathophysiology.

Topiramate is marketed under several trade names, including Topamax, Trokendi XR, and Qudexy XR.

Topamax was originally developed by Janssen Pharmaceuticals, while generic versions are manufactured by multiple pharmaceutical companies worldwide.

The complete generic name is topiramate.

Common brand names include Topamax, Trokendi XR, and Qudexy XR.

Topiramate is manufactured in FDA-, EMA-, and MHRA-approved pharmaceutical facilities across the USA, EU, and UK, with production handled by both innovator and generic manufacturers.

Yes, Topiramate is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Topiramate is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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