TAF + Emtricitabine + Elvitegravir + Cobicistat Suppliers & Bulk Manufacturers

Available Forms: Tablet

Available Strengths: Elvitegravir – 150 mg + Cobicistat – 150 mg + Emtricitabine – 200 mg + TAF – 10 mg

Reference Brands: Genvoya(US & EU)

Category: Anti Viral

Elvitegravir, cobicistat, emtricitabine and tenofovir alafenamide (150/150/200/10 mg) single-tablet HIV-1 regimen. For importers, distributors, HIV clinics and hospital pharmacies sourcing a once-daily integrase-based combination.

Product Description:

This fixed-dose tablet combines four antiretrovirals into one complete daily regimen for HIV-1. Elvitegravir 150 mg is an integrase strand transfer inhibitor that stops viral DNA joining the host genome. Cobicistat 150 mg has no antiviral activity; it inhibits CYP3A and keeps elvitegravir levels high enough for once-daily dosing. Emtricitabine 200 mg and tenofovir alafenamide 10 mg form the nucleoside backbone. Tenofovir alafenamide delivers tenofovir into cells at a much lower dose than the older disoproxil salt, so blood levels of tenofovir are lower.

The tablet is used in adults and in children above a label-defined minimum weight, to start treatment or to switch while virologically suppressed, where no resistance to the components is known. It is taken once a day with food. Cobicistat drives many interactions: rifampicin and St John's wort are contraindicated, and many statins and sedatives need checking. Antacids and mineral supplements are separated from the dose. Cobicistat raises serum creatinine slightly without changing true kidney function. It is not recommended in pregnancy.

Sourcing notes. This combination is prescription-only and registered nationally. WHO guidelines favour dolutegravir-based regimens for most programmes, so demand comes mainly from markets following US or European guidance. Confirm patent and data exclusivity status before planning a generic registration, and check for bioequivalence on all four components. Tablets come in HDPE bottles with a desiccant and must stay in the original container. Request the batch CoA, the GMP certificate, a CoPP and zone IVb stability data. State tablets per bottle and label languages.