Sulfadoxine + Pyrimethamine (Sp) – Tablets Suppliers & Bulk Manufacturers

Available Forms: Tablet

Available Strengths: 500 mg sulfadoxine + 25 mg pyrimethamine; 500 mg + 75 mg

Reference Brands: Generic formulations

Category: Medical Aid

Sulfadoxine inhibits bacterial dihydropteroate synthase, while pyrimethamine blocks dihydrofolate reductase, disrupting folate synthesis in malaria parasites. This combination effectively kills Plasmodium falciparum, providing rapid malaria prophylaxis and treatment. Benefits include high efficacy, synergy against resistant strains, and simplified dosing in endemic regions.

Product Description: Sulfadoxine + Pyrimethamine (SP) tablets are approved for malaria treatment and prophylaxis in the EU and US, mainly in endemic regions. In the EU, brands like Fansidar are regulated by EMA, supported by dossiers demonstrating safety, efficacy, and manufacturing standards. In the US, approval is limited; primarily used in travel medicine and imported cases, with no specific brand approval. Both regions require detailed dossiers including clinical trial data, quality assurance, and pharmacovigilance plans for approval and safety monitoring. For expert assistance with regulatory dossiers, compliance, and registration, visit PharmaTradz. We support seamless market access for sulfadoxine/pyrimethamine, ensuring adherence to European and US standards for safe, effective malaria therapy.