Succinylcholine Chloride 20 mg/mL, 100 mg/mL Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 20 mg/mL, 100 mg/mL

Reference Brands: Anectine (USA), Quelicin (USA)

Category: Anaesthetics

Succinylcholine Chloride is a Anaesthetics product available as Injection in strengths 20 mg/mL, 100 mg/mL. It corresponds to the reference brands Anectine (USA), Quelicin (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Succinylcholine Chloride is the chloride salt form of succinylcholine, a quaternary ammonium compound that functions as a rapid-acting depolarizing neuromuscular blocking agent. It is primarily used to induce short-term skeletal muscle relaxation during general anesthesia, rapid sequence intubation, and certain emergency or surgical procedures where quick onset and brief duration of action are essential. Structurally similar to acetylcholine, Succinylcholine Chloride binds to nicotinic acetylcholine receptors at the neuromuscular junction and opens ligand-gated ion channels, leading to depolarization of the motor end plate.

Unlike acetylcholine, succinylcholine is resistant to breakdown by acetylcholinesterase at the synaptic cleft, resulting in prolonged depolarization. This sustained depolarized state prevents further neuromuscular transmission, initially causing transient muscle fasciculations followed by skeletal muscle relaxation and flaccid paralysis. The drug’s effects are short-lived due to rapid hydrolysis by plasma pseudocholinesterase, allowing for quick recovery of muscle function.

Because Succinylcholine Chloride causes complete muscle paralysis, it must be administered only in controlled medical environments with adequate airway management and ventilatory support. Its predictable onset and brief duration make it especially valuable in anesthesia and emergency medicine when rapid, temporary neuromuscular blockade is required.