Selumetinib 10mg, 25mg Suppliers & Bulk Manufacturers
Available Forms: Capsules
Available Strengths: 10mg, 25mg
Reference Brands: Koselugo (USA)
Category: Neurology
Selumetinib is a selective inhibitor of the enzymes MEK1 and MEK2, which are part of a signalling pathway involved in cell growth and division. By blocking MEK1/2, selumetinib helps reduce abnormal growth of nerve-sheath tumors (plexiform neurofibromas) in people with genetic disorder Neurofibromatosis type 1 (NF1). Koselugo is indicated for patients (children and now adults) with symptomatic, inoperable plexiform neurofibromas — helping shrink tumor volume or slow growth when surgical removal is not feasible.
Selumetinib — third party manufacturing & bulk supply
Selumetinib 10mg, 25mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Selumetinib is supplied as Capsules — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Selumetinib listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for Selumetinib →Frequently Asked Questions
Selumetinib is used to treat neurofibromatosis type 1 (NF1) in children with inoperable plexiform neurofibromas. It works by inhibiting the MEK1 and MEK2 enzymes in the RAS/MAPK pathway, which helps reduce tumor growth.
Selumetinib is made from the active pharmaceutical ingredient selumetinib hydrochloride, a small-molecule MEK inhibitor.
The trade name is Koselugo.
Koselugo is manufactured by AstraZeneca.
The generic name is selumetinib hydrochloride.
The primary brand name is Koselugo.
It is manufactured in approved pharmaceutical facilities in Europe and the USA, depending on regulatory approvals.
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