Available Forms: Injection
Available Strengths: 2,500 units/0.5 mL, 5,000 units/1 mL
Reference Brands: Myobloc (USA)
Category: Neurology
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Product Description:
MYOBLOC (rimabotulinumtoxinB) injection is a sterile liquid formulation containing a purified botulinum neurotoxin designed for therapeutic use in controlled medical settings. It acts at the neuromuscular junction, where it inhibits the release of acetylcholine, leading to temporary flaccid paralysis of targeted muscles. This mechanism makes it effective for the management of specific neuromuscular conditions that require localized muscle relaxation.
The active neurotoxin is produced through the fermentation of Clostridium botulinum type B, specifically the Bean strain. In its natural state, the neurotoxin exists as a complex in noncovalent association with hemagglutinin and nonhemagglutinin proteins, which help maintain stability during processing. Following fermentation, the neurotoxin complex is carefully recovered and subjected to multiple purification steps.
RimabotulinumtoxinB is used for the treatment of cervical dystonia to reduce the severity of abnormal head position and neck pain. It is also used to manage chronic sialorrhea (excessive salivation) in adults.
RimabotulinumtoxinB is made from purified botulinum neurotoxin type B produced by fermentation of Clostridium botulinum, followed by specialized purification processes.
The trade name of rimabotulinumtoxinB is Myobloc in the USA and NeuroBloc in several EU countries.
RimabotulinumtoxinB is manufactured and marketed by US WorldMeds (formerly Solstice Neurosciences).
The generic name of the product is rimabotulinumtoxinB.
The brand name is Myobloc (USA) and NeuroBloc (EU).
RimabotulinumtoxinB is manufactured in GMP-compliant pharmaceutical facilities in the USA and EU, following strict regulatory and quality standards.
Strength: 125 mg/mL, 200 mg, 250 mg, 300 mg, 500 mg, 100 mg/mL
Form: Tablet / Capsule/ Injection / Oral syrup
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