Remdesivir Suppliers & Bulk Manufacturers

Available Forms: Lyophilized powder for IV & Injection

Available Strengths: Powder(100 mg/vial); Injection: 100 mg/20 mL (5 mg/mL)

Reference Brands: Veklury® (EU & US)

Category: Anti Covid Medicines

Remdesivir 100 mg lyophilised powder and 100 mg/20 mL concentrate for intravenous infusion, an antiviral for COVID-19. For hospitals, tender suppliers and licensed importers in markets where the licence and registration position allows supply.

Product Description:

Remdesivir is a nucleotide analogue prodrug. Inside cells it becomes an active triphosphate that the SARS-CoV-2 RNA polymerase takes up in place of a natural building block, which halts viral RNA synthesis. Poor oral bioavailability means it is given only intravenously. This page lists a 100 mg vial of lyophilised powder, reconstituted with sterile water and diluted in sodium chloride 0.9%, and a 100 mg/20 mL (5 mg/mL) concentrate that only needs dilution. The powder is more common because it needs no refrigeration.

Remdesivir is approved for COVID-19 in hospitalised adults and children, particularly those with pneumonia needing oxygen, and as a three-day course for high-risk patients not needing oxygen. Adults usually receive 200 mg on day one, then 100 mg once daily, each infused over 30 to 120 minutes. Liver function and prothrombin time are checked before and during treatment. Infusion and hypersensitivity reactions can occur, so patients are observed. Chloroquine and hydroxychloroquine are avoided because they can reduce its antiviral activity.

Sourcing notes. Remdesivir remains under patent in many countries, and some generic versions may be sold only in territories covered by voluntary licences, so confirm the licence and patent position for your market first. It is a prescription-only hospital medicine needing registration, emergency authorisation, or a tender or named-patient route. Store the powder below 30 °C and the concentrate at 2-8 °C, as labelled. Ask for the CTD or ACTD dossier, Zone IVb stability data, a certificate of analysis for each batch, GMP certificate and CoPP.