Ramipril / Hydrochlorothiazide Tablets bulk supplier for pharma manufacturers

Ramipril / Hydrochlorothiazide Tablets 2.5mg+12.5mg, 5mg+25mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 2.5mg+12.5mg, 5mg+25mg

Reference Brands: Tritazide (EU)

Ramipril and hydrochlorothiazide tablets, 2.5/12.5 mg and 5/25 mg, an ACE inhibitor and thiazide combination for hypertension not controlled on one drug. For importers, distributors, hospitals and pharmacies.

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Product Description:

This tablet combines ramipril, an ACE inhibitor that lowers angiotensin II and relaxes blood vessels, with hydrochlorothiazide, a thiazide diuretic that increases sodium and water loss. The two partly offset each other's effect on potassium. The listed strengths, 2.5 mg/12.5 mg and 5 mg/25 mg, let a patient stabilised on the separate drugs switch to one tablet a day. Ramipril is chemically fragile and can cyclise to a diketopiperazine impurity under heat and moisture, so formulation and packaging quality matter.

It is licensed for hypertension not controlled by ramipril or hydrochlorothiazide alone; it is not a starting therapy. It is taken once daily, usually in the morning. Pregnancy, a history of angioedema, severe renal impairment and anuria are contraindications, and dual blockade with an angiotensin receptor blocker or aliskiren is avoided. Lithium levels rise, and NSAIDs blunt the effect and stress the kidneys. Pharmacists check potassium, sodium, creatinine and uric acid. Long-term hydrochlorothiazide carries a warning about non-melanoma skin cancer.

Sourcing notes. Ask for stability data that track ramipril diketopiperazine and other degradants through shelf life, with zone IVb results if you serve hot humid markets. Alu-alu blisters give the moisture protection this product needs; storage is at room temperature, with no cold chain. Each batch CoA should show assay, content uniformity, dissolution and related substances for both actives. Regulators expect a nitrosamine risk assessment for chemically synthesised medicines, so request it, along with the GMP certificate, a CoPP and bioequivalence data. Specify both strengths, blister count and language.

Ramipril / Hydrochlorothiazide Tablets — third party manufacturing & bulk supply

Ramipril / Hydrochlorothiazide Tablets 2.5mg+12.5mg, 5mg+25mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Ramipril / Hydrochlorothiazide Tablets is supplied as Tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Ramipril / Hydrochlorothiazide Tablets listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Usually answered within 48 hours, with matched manufacturers, indicative prices and document status.

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Frequently Asked Questions

Ramipril / Hydrochlorothiazide is used to treat hypertension (high blood pressure) in patients who require combination therapy. It helps lower blood pressure, reducing the risk of heart attack, stroke, and other cardiovascular complications.

It is a combination of Ramipril, an ACE inhibitor that blocks the formation of angiotensin II to relax blood vessels, and Hydrochlorothiazide, a thiazide diuretic that increases the excretion of sodium and water through the kidneys, lowering blood volume and blood pressure.

This combination is marketed under various trade names depending on the manufacturer and region.

Several companies make it, in India and elsewhere. Tell us your market and we will match you with licensed makers whose documents fit.

The generic name is Ramipril + Hydrochlorothiazide.

Brand names vary by region and manufacturer, including Ramace H, Tritace H, and other regional brands.

It is manufactured globally, particularly in India, Europe, and other regions, by multiple pharmaceutical companies under approved regulatory standards.