Propranolol Extended-Release Capsules 60 mg, 80 mg, 120 mg, 160 mg Suppliers & Bulk Manufacturers

Available Forms: Extended-Release Capsules

Available Strengths: 60 mg, 80 mg, 120 mg, 160 mg

Reference Brands: Inderal LA®

Category: Antipsychotropic Drugs

Propranolol extended-release capsules 60 mg, 80 mg, 120 mg and 160 mg for once-daily beta-blocker therapy in stable patients. For importers, distributors, hospital pharmacies and tender buyers.

Product Description:

Propranolol extended-release capsules contain the same non-selective beta-blocker as conventional tablets, in a form built for once-daily dosing. Each capsule holds coated pellets that release propranolol steadily through the day, giving flatter blood levels and a simpler routine than tablets. This page covers 60 mg, 80 mg, 120 mg and 160 mg strengths. The trade-off is flexibility: these capsules suit patients stable on a known dose, not acute situations. Chewing or crushing the pellets would defeat the release design.

The capsules are used for long-term conditions: hypertension, angina, migraine prophylaxis, essential tremor and, in some labels, hypertrophic subaortic stenosis and anxiety. A key practical point is that the extended-release capsule is not a milligram-for-milligram substitute for immediate-release tablets, because blood levels differ, so patients changing forms may need re-titration. The familiar beta-blocker contraindications still apply, among them asthma, bradycardia, heart block and decompensated heart failure. Withdrawal must be gradual.

Sourcing notes. These capsules are prescription-only. For a modified-release product the CTD or ACTD dossier should include bioequivalence studies under fasting and fed conditions, and the batch CoA should report dissolution at several time points, not one. Ask for long-term stability at 30 °C/75% RH where the capsules go to Zone IVb markets, since gelatin shells and pellet coatings both react to humidity. Bottles with desiccant are usual, stored below 30 °C with no cold chain. Request the GMP certificate, a CoPP and a TSE/BSE statement for the capsule shell, and name the local reference product the capsules must match.