Phenelzine Tablets Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 15 mg

Reference Brands: Nardil®(US)

Category: Antipsychotropic Drugs

Phenelzine is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) that works by inhibiting the breakdown of serotonin, norepinephrine, and dopamine, thereby increasing their levels in the brain. It is primarily used to treat major depressive disorder (MDD), especially in patients who have not responded to other treatments. Due to its mechanism, dietary restrictions (e.g., avoiding tyramine-rich foods) and careful monitoring for drug interactions are essential to prevent serious adverse effects such as hypertensive crisis.

Product Description: Phenelzine tablets are FDA-approved in the United States for the treatment of major depressive disorder (MDD), particularly in patients unresponsive to other therapies. As a non-selective, irreversible MAOI, phenelzine requires strict regulatory oversight due to risks such as hypertensive crisis and serotonin syndrome. U.S. regulations mandate Boxed Warnings, patient guides, and GMP-compliant manufacturing. Bioequivalence data is needed for generic versions. In the European Union, phenelzine is either rarely used or available through special access programs, due to safety concerns and dietary restrictions. EU dossiers, if applicable, must include Risk Management Plans (RMPs) and robust pharmacovigilance. For global sourcing, visit Pharmatradz.com.