Obeticholic Acid 5 mg, 10 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 5 mg, 10 mg

Reference Brands: Ocaliva (USA)

Category: Critical Care

Obeticholic Acid is a Critical Care product available as Tablets in strengths 5 mg, 10 mg. It corresponds to the reference brand Ocaliva (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Obeticholic acid is a medication prescribed for the management of primary biliary cholangitis (PBC), a chronic liver disease characterized by progressive bile duct damage and liver dysfunction. It is a semi-synthetic bile acid analogue, chemically known as 6α-ethyl-chenodeoxycholic acid, that works by activating the farnesoid X receptor (FXR) in the liver. Activation of FXR helps regulate bile acid synthesis and transport, reduces bile acid accumulation, and supports liver function.

Sold under the brand name Ocaliva, obeticholic acid is typically used in adults who have not responded adequately to ursodeoxycholic acid (UDCA) or are unable to tolerate UDCA. The medication is available as oral tablets in strengths of 5 mg and 10 mg, allowing for flexible dosing based on patient needs.

Obeticholic acid therapy requires careful monitoring due to potential liver-related adverse effects, and dosing must be individualized according to disease severity and patient response. It is an important treatment option in critical care for patients with PBC, helping healthcare professionals provide targeted, safe, and effective management. Intercept Pharmaceuticals Inc. holds the rights to Ocaliva outside Japan and China, where it is licensed to Dainippon Sumitomo Pharma.