Nortriptyline Oral Solution 10 mg/5 mL Suppliers & Bulk Manufacturers

Available Forms: Oral Solution

Available Strengths: 10 mg/5 mL

Reference Brands: Pamelor®(US); Nortrilen®(EU)

Category: Antipsychotropic Drugs

Nortriptyline oral solution 10 mg/5 mL, a liquid tricyclic antidepressant for patients who cannot take capsules. For importers, hospital pharmacies and distributors sourcing registered stock with dossier support.

Product Description:

Nortriptyline oral solution is the liquid form of a tricyclic antidepressant, at 10 mg in each 5 mL. Like the capsules, it works by blocking the reuptake of noradrenaline and, more weakly, serotonin. The liquid exists for people who cannot swallow capsules: frail older adults, patients with swallowing problems after stroke, and those fed through tubes. It also allows doses no capsule offers.

It is used for depression, and off-label for neuropathic pain where a liquid is easier to give. The same safety points apply as for the solid form: the boxed warning on suicidal thinking in under-25s, care in heart disease and epilepsy, no use with MAO inhibitors, and raised levels with CYP2D6 inhibitors. Some oral solutions contain alcohol and sorbitol, so check the excipient list for children, pregnant women and people with liver disease. Plasma level monitoring is sometimes used.

Sourcing notes. This is a prescription-only medicine. Liquid dossiers need more than solid ones: ask for stability data on the opened bottle, preservative efficacy testing and microbial limits, plus Zone IVb data for hot climates. Amber glass or PET bottles protect the product from light, and a child-resistant closure is expected in many markets. Confirm that a dosing syringe or cup is included. Request a CoA per batch with assay, related substances and microbial results, the GMP certificate, a CoPP and the CTD or ACTD format you need. Give bottle size and target country when you enquire.