Nortriptyline Capsules 10 mg, 25 mg, 50 mg, 75 mg Suppliers & Bulk Manufacturers

Available Forms: Capsules

Available Strengths: 10 mg, 25 mg, 50 mg, 75 mg

Reference Brands: Pamelor®(US); Nortrilen®(EU)

Category: Antipsychotropic Drugs

Nortriptyline hard capsules 10 mg, 25 mg, 50 mg and 75 mg, a prescription tricyclic antidepressant. For importers, distributors and hospital pharmacies sourcing registered generic stock with full dossier support.

Product Description:

Nortriptyline capsules are a tricyclic antidepressant in solid oral form. The molecule raises noradrenaline and, to a lesser degree, serotonin levels at nerve endings by blocking their reuptake. Compared with amitriptyline, from which it is derived, it tends to cause less sedation and less postural drop in blood pressure. This page lists hard capsules of 10 mg, 25 mg, 50 mg and 75 mg. The range lets prescribers start low, which suits older patients.

The licensed use is depression. In daily practice nortriptyline capsules are also widely prescribed, outside the licence in many countries, for neuropathic pain. Doses are built up over days to weeks, often given once daily at bedtime. Pharmacists will look for the boxed warning on suicidal thoughts in children and young adults, and for advice on cardiac conduction, seizures and anticholinergic effects such as dry mouth and constipation. MAO inhibitors are contraindicated, and CYP2D6 inhibitors such as fluoxetine or paroxetine raise levels. Overdose is dangerous, so packs are often kept small.

Sourcing notes. Nortriptyline capsules are prescription-only medicines. Ask for a CTD or ACTD dossier that includes bioequivalence data against a recognised reference product and stability data for Zone IVb where you supply tropical markets. Capsules usually come in PVC/PVDC or alu-alu blisters, or in HDPE bottles for pharmacy dispensing. Store below 25 °C, dry and away from light. Request a CoA per batch, the GMP certificate of the manufacturing site, a CoPP and the API supplier's nitrosamine assessment. Specify strengths, pack count and shelf life in your enquiry.