Nifurtimox 30 mg, 120 mg Suppliers & Bulk Manufacturers

Available Forms: Tablet

Available Strengths: 30 mg, 120 mg

Reference Brands: Lampit (USA)

Category: Anti Viral

Nifurtimox is an antiprotozoal medicine used to treat parasitic infections, including Chagas disease and African trypanosomiasis (sleeping sickness). It works by generating toxic radicals inside the parasite, damaging its DNA and killing it.

Product Description:

Nifurtimox is a nitrofuran antiparasitic, not an antiviral. Inside the parasite it is reduced to nitro radicals that generate reactive oxygen species; Trypanosoma cruzi has weak defences against oxidative stress compared with human cells, which gives the drug its selectivity.

It is used to treat Chagas disease, caused by Trypanosoma cruzi and transmitted by triatomine bugs across Latin America, with several million people infected. Treatment is most effective in the acute phase and in children, where cure rates are high; in chronic disease the benefit is smaller and debated, though treatment is recommended in younger adults to slow progression to the cardiomyopathy and megacolon that cause most of the harm. Courses run sixty to ninety days and adverse effects are common — nausea, weight loss, headache, and peripheral neuropathy with longer use — which makes completion a real challenge. A paediatric dispersible tablet improved dosing in children.

Sourcing notes. Access has historically depended on donation programmes and WHO channels rather than commercial distribution, and registration outside endemic countries is limited. Benznidazole is the alternative first-line agent. This product belongs under antiparasitic, not antiviral.