Neostigmine Methylsulfate 0.5 mg/mL, 1 mg/ml Suppliers & Bulk Manufacturers
Available Forms: Injection
Available Strengths: 0.5 mg/mL, 1 mg/ml
Reference Brands: Prostigmin (USA), Neostigmine (USA)
Category: Neurology
Neostigmine Methylsulfate is a Neurology product available as Injection in strengths 0.5 mg/mL, 1 mg/ml. It corresponds to the reference brands Prostigmin (USA), Neostigmine (USA). Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.
Product Description:
Neostigmine is a medication used to improve neuromuscular function and manage specific medical conditions, marketed under the brand name Bloxiverz and other regional brands. It is commonly used to treat myasthenia gravis, a chronic autoimmune disorder that causes muscle weakness, as well as Ogilvie syndrome, and urinary retention when there is no physical blockage. Additionally, neostigmine is used in anesthesia to reverse the effects of non-depolarizing neuromuscular blocking agents after surgery, helping restore normal muscle function.
Neostigmine works as a reversible cholinesterase inhibitor, increasing the concentration of acetylcholine at the neuromuscular junction. This enhances communication between nerves and muscles, improving muscle contraction and strength. The medication is administered via injection into a vein, muscle, or under the skin, with effects typically appearing within 30 minutes and lasting up to 4 hours.
Neostigmine provides a safe and effective option for clinicians to manage neuromuscular disorders, improve postoperative recovery, and address complications like urinary retention. Its rapid onset and predictable duration make it suitable for both acute interventions and ongoing management under careful medical supervision.
Neostigmine Methylsulfate — third party manufacturing & bulk supply
Neostigmine Methylsulfate 0.5 mg/mL, 1 mg/ml is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Neostigmine Methylsulfate is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Neostigmine Methylsulfate listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for Neostigmine Methylsulfate →Frequently Asked Questions
Neostigmine methylsulfate is used to improve neuromuscular transmission in patients with myasthenia gravis and other conditions causing muscle weakness. It is also used to reverse the effects of non-depolarizing neuromuscular blockers after surgery.
Neostigmine methylsulfate is a synthetic reversible cholinesterase inhibitor. It is chemically manufactured and is not derived from natural or biological sources.
Neostigmine methylsulfate is marketed under trade names such as Prostigmin and Neostigmine Methylsulfate Injection.
Neostigmine methylsulfate is manufactured and commercialized by multiple pharmaceutical companies, including Pfizer (Prostigmin) and other authorized generic manufacturers, following US FDA and EU GMP regulations.
The generic name is neostigmine methylsulfate.
The brand names include Prostigmin and Neostigmine Methylsulfate Injection.
Neostigmine methylsulfate is manufactured in facilities compliant with US FDA and EU GMP standards, including production sites in the USA, Europe, and other regulated markets.
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