naltrexone hydrochloride + bupropion hydrochloride ER tablets bulk supplier for pharma manufacturers

Naltrexone Hydrochloride + Bupropion Hydrochloride ER Tablets Suppliers & Bulk Manufacturers

Available Forms: ER tablets

Available Strengths: 8 mg naltrexone hydrochloride / 90 mg bupropion hydrochloride

Reference Brands: Contrave(US & EU)

Naltrexone hydrochloride 8 mg with bupropion hydrochloride 90 mg extended-release tablets, a prescription weight-management medicine, for importers, distributors and pharmacy chains in registered markets.

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Product Description:

Naltrexone and bupropion extended-release tablets combine two established drugs for chronic weight management. Each tablet holds 8 mg naltrexone hydrochloride and 90 mg bupropion hydrochloride. Bupropion blocks the reuptake of dopamine and noradrenaline, and naltrexone is an opioid antagonist. Together they act on appetite centres in the hypothalamus and on reward circuits, which reduces hunger and cravings. The extended-release matrix keeps peak bupropion levels down, so the tablets are swallowed whole, never cut, crushed or chewed.

It is prescribed for adults with obesity, or overweight with a weight-related condition, alongside diet and exercise. The dose is built up over four weeks to two tablets twice daily, and treatment stops if weight loss is too modest after about 12 weeks on the full dose. Bupropion lowers the seizure threshold, so it is not used in epilepsy, eating disorders or abrupt alcohol or sedative withdrawal. Opioids, MAOIs and high-fat meals are avoided, and the antidepressant suicidality warning applies.

Sourcing notes. This is a prescription-only medicine, and a generic needs bioequivalence on both components. Ask for a CTD or ACTD dossier with dissolution profiles showing the extended release is consistent between batches, plus zone IVb stability for hot, humid markets. Bupropion is sensitive to heat and moisture, so check for a sealed bottle with desiccant or a high-barrier blister. Request a CoA for each batch, the finished-product GMP certificate and a CoPP, and state the pack count and target market.

Naltrexone Hydrochloride + Bupropion Hydrochloride ER Tablets — third party manufacturing & bulk supply

Naltrexone Hydrochloride + Bupropion Hydrochloride ER Tablets is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.

Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.

Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Naltrexone Hydrochloride + Bupropion Hydrochloride ER Tablets is supplied as ER tablets — an oral solid dosage form, so the indicative MOQ is 200,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Naltrexone Hydrochloride + Bupropion Hydrochloride ER Tablets listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

naltrexone hydrochloride + bupropion hydrochloride ER tablets is listed as ER tablets in 8 mg naltrexone hydrochloride / 90 mg bupropion hydrochloride. Further strengths and pack presentations are confirmed with the manufacturer at RFQ stage.

naltrexone hydrochloride + bupropion hydrochloride ER tablets is referenced against Contrave(US & EU). Reference brands are shown for identification only and remain the property of their respective trademark owners.