Methylcobalamine + Pyridoxine Hcl + Niacinamide + D Panethol 1000mcg, 100mg, 100mg, 50mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 1000mcg, 100mg, 100mg, 50mg

Reference Brands:

Category: Nutraceuticals

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Product Description:

This injection combines methylcobalamin, the active coenzyme form of vitamin B12; pyridoxine, vitamin B6; niacinamide, a form of vitamin B3; and D-panthenol, the alcohol form of pantothenic acid (vitamin B5). B12 and B6 are needed for nerve function and myelin maintenance, and B12 for DNA synthesis and red blood cell formation. Niacinamide and pantothenic acid are cofactors in energy metabolism.

Injectable B-vitamin combinations of this kind are used, mainly in South Asia, for peripheral neuropathy, including diabetic neuropathy, and for vitamin B deficiency. Injection is justified when absorption is impaired, as in pernicious anaemia, where intramuscular B12 is standard. The other components are well absorbed orally, and evidence that injecting them improves neuropathy beyond correcting deficiency is limited. The underlying cause of neuropathy should always be investigated. Injection-site pain and rare hypersensitivity reactions occur. Long-term high-dose pyridoxine can itself cause neuropathy.

Sourcing notes. A fixed-dose combination registered mainly in India and neighbouring markets. Several regulators have reviewed vitamin combination injections for rationality, so confirm acceptability in the destination market. Methylcobalamin is light-sensitive, so amber ampoules and light-protective packaging are required.