Metformin Extended-Release (Er/Xr) Tablets 500 mg, 750 mg, 1000 mg Suppliers & Bulk Manufacturers
Available Forms: Extended-Release (ER/XR) Tablets
Available Strengths: 500 mg, 750 mg, 1000 mg
Reference Brands: Glucophage XR®, Fortamet®, Glumetza®
Category: Diabetes
Metformin extended-release tablets (500, 750 and 1,000 mg) are taken once daily with the evening meal for type 2 diabetes. The slow-release form causes fewer stomach side effects than standard metformin and makes treatment simpler. Reference brands include Glucophage XR and Glumetza. PharmaTradz sources it for importers, hospitals and tenders, and shares GMP certificates and CoA before you commit.
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Product Description:
Metformin Extended-Release (ER/XR) tablets are approved in both the USA and EU for the treatment of type 2 diabetes mellitus. In the USA, they are regulated under the FDA’s NDA and ANDA pathways, with several generic approvals available. Common brands include Glucophage XR and Fortamet. In the EU, Metformin ER is authorized via national procedures and is included in multiple Member States' formularies. ER formulations improve gastrointestinal tolerability and enhance patient adherence by allowing once-daily dosing. Pharmatradz.com supports global buyers in sourcing Metformin ER tablets from GMP-certified manufacturers compliant with FDA and EMA quality standards.
Metformin Extended-Release (Er/Xr) Tablets — third party manufacturing & bulk supply
Metformin Extended-Release (Er/Xr) Tablets 500 mg, 750 mg, 1000 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
Metformin Extended-Release (Er/Xr) Tablets is supplied as Extended-Release (ER/XR) Tablets — supplied in more than one dosage form, each with its own manufacturing economics, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of Metformin Extended-Release (Er/Xr) Tablets listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for Metformin Extended-Release (Er/Xr) Table... →Usually answered within 48 hours, with matched manufacturers, indicative prices and document status.
Frequently Asked Questions
Metformin Tablets are used to manage type 2 diabetes mellitus. They help lower blood glucose levels by improving insulin sensitivity, decreasing hepatic glucose production, and enhancing peripheral glucose uptake. Metformin is often used as a first-line therapy in adults and children with type 2 diabetes and may be combined with other antidiabetic medications when needed.
The tablets contain metformin hydrochloride, a biguanide compound that acts on the liver and peripheral tissues to reduce glucose production and improve insulin utilization. Extended-release formulations provide a slower absorption for sustained blood sugar control.
Common trade names include Glucophage, Glumetza, Riomet, Obimet, and Siofor, along with various generic formulations worldwide.
Glucophage and Glumetza are marketed by Bristol-Myers Squibb / Merck, Riomet by Merck, and Obimet and Siofor by multiple regional manufacturers. Generic metformin is produced globally by numerous pharmaceutical companies.
The generic name is metformin hydrochloride.
Brand names include Glucophage, Glumetza, Riomet, Obimet, Siofor, and several regional generics.
It is manufactured in GMP-certified pharmaceutical facilities across the USA, Europe, India, and Latin America.
It causes less diarrhoea and nausea than immediate-release metformin and is taken once daily with the evening meal.
Usually 2,000 mg a day (some products allow 2,500 mg).
Several metformin XR batches were recalled from 2020 because of NDMA impurity. Buyers now ask for nitrosamine risk assessments and test results.
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