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Metformin Extended-Release (ER/XR) Tablets bulk supplier for pharma manufacturers

Metformin Extended-Release (Er/Xr) Tablets 500 mg, 750 mg, 1000 mg Suppliers & Bulk Manufacturers

Available Forms: Extended-Release (ER/XR) Tablets

Available Strengths: 500 mg, 750 mg, 1000 mg

Reference Brands: Glucophage XR®, Fortamet®, Glumetza®

Category: Diabetes

Metformin ER/XR reduces hepatic glucose production, enhances insulin sensitivity, and improves peripheral glucose uptake. Its extended-release formulation ensures gradual drug release, minimizing gastrointestinal side effects. Benefits include effective blood sugar control, improved adherence with once-daily dosing, and weight neutrality, making it a first-line therapy for type 2 diabetes management.

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📘 Sourcing Guide

Product Description:

Metformin Extended-Release (ER/XR) tablets are approved in both the USA and EU for the treatment of type 2 diabetes mellitus. In the USA, they are regulated under the FDA’s NDA and ANDA pathways, with several generic approvals available. Common brands include Glucophage XR and Fortamet. In the EU, Metformin ER is authorized via national procedures and is included in multiple Member States' formularies. ER formulations improve gastrointestinal tolerability and enhance patient adherence by allowing once-daily dosing. Pharmatradz.com supports global buyers in sourcing Metformin ER tablets from GMP-certified manufacturers compliant with FDA and EMA quality standards.

Metformin Extended-Release (Er/Xr) Tablets — third party manufacturing & bulk supply

Metformin Extended-Release (Er/Xr) Tablets 500 mg, 750 mg, 1000 mg is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

What to include when you enquire

  • Destination market — determines which manufacturers hold the right site-level approvals
  • First order quantity and estimated annual volume
  • Whether you need a registration dossier or the product is already registered
  • Packaging, labelling and language requirements
  • Incoterms and required shelf life

Manufacturers of Metformin Extended-Release (Er/Xr) Tablets listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding. Narcotic drugs and controlled substances are supplied strictly against valid import and export permits issued by the competent authorities.

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Frequently Asked Questions

Metformin Tablets are used to manage type 2 diabetes mellitus. They help lower blood glucose levels by improving insulin sensitivity, decreasing hepatic glucose production, and enhancing peripheral glucose uptake. Metformin is often used as a first-line therapy in adults and children with type 2 diabetes and may be combined with other antidiabetic medications when needed.

The tablets contain metformin hydrochloride, a biguanide compound that acts on the liver and peripheral tissues to reduce glucose production and improve insulin utilization. Extended-release formulations provide a slower absorption for sustained blood sugar control.

Common trade names include Glucophage, Glumetza, Riomet, Obimet, and Siofor, along with various generic formulations worldwide.

Glucophage and Glumetza are marketed by Bristol-Myers Squibb / Merck, Riomet by Merck, and Obimet and Siofor by multiple regional manufacturers. Generic metformin is produced globally by numerous pharmaceutical companies.

The generic name is metformin hydrochloride.

Brand names include Glucophage, Glumetza, Riomet, Obimet, Siofor, and several regional generics.

It is manufactured in GMP-certified pharmaceutical facilities across the USA, Europe, India, and Latin America.

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