Loperamide – Tablets/Capsules 2 mg Suppliers & Bulk Manufacturers

Available Forms: Tablets/capsules

Available Strengths: 2 mg

Reference Brands: Imodium(US & EU)

Category: Medical Aid

Loperamide hydrochloride 2 mg tablets and capsules, a gut-selective opioid antidiarrhoeal for short-term use. For importers, distributors, pharmacy chains and hospital buyers sourcing OTC or prescription-labelled packs.

Product Description:

Loperamide is a synthetic opioid that acts on mu-opioid receptors in the gut wall. It slows intestinal transit and increases absorption of water and salts, so stools become firmer and less frequent. Very little reaches the brain at normal doses, because P-glycoprotein pumps it back out. This page covers 2 mg tablets and hard capsules.

It gives short-term symptomatic control of acute diarrhoea in adults and older children, and is prescribed for some chronic diarrhoeas. Oral rehydration remains the foundation of care. The usual adult regimen is 4 mg at first, then 2 mg after each loose stool, up to a daily maximum that is lower for self-medication. It is not used in bloody diarrhoea with fever, acute ulcerative colitis, antibiotic-associated colitis or where slowing the bowel risks ileus. It is contraindicated in young children. Misuse at very high doses has caused serious heart rhythm problems, and CYP3A4 or P-glycoprotein inhibitors raise its levels.

Sourcing notes. Loperamide is sold over the counter in many markets in limited pack sizes and on prescription in larger ones, so confirm which licence you need before fixing packs. Some regulators want blisters with restricted counts. A CTD or ACTD dossier with bioequivalence data and zone IVb stability is the usual standard. Tablets and capsules ship at room temperature in moisture-protective blisters. Each batch should come with a CoA, backed by a GMP certificate and a CoPP. In the enquiry, state tablet or capsule, units per carton, OTC or prescription labelling and shelf life on arrival.

Also known as: loperamida (Spanish), lopéramide (French), Loperamid (German), лоперамид (Russian), لوبيراميد (Arabic), 洛哌丁胺 (Chinese), ロペラミド (Japanese), 로페라미드 (Korean).