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Lacosamide bulk supplier for pharma manufacturers

Lacosamide Suppliers & Bulk Manufacturers

Available Forms: Tablets/ Oral Solution / Injectable

Available Strengths: 50 mg, 100 mg, 150 mg, 200 mg , 10 mg/mL, 200 mg/20 mL

Reference Brands: Vimpat (USA/EU), Motpoly XR (USA),

Category: Neurology

Lacosamide is an anti-epileptic (anticonvulsant) medication used for the treatment of partial-onset (focal) seizures in adults and children. It works by enhancing the slow inactivation of voltage-gated sodium channels, stabilizing hyperexcitable neuronal membranes, and reducing repetitive neuronal firing. Lacosamide may also interact with CRMP-2 (collapsin response mediator protein-2), contributing to its anti-seizure effects.

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Product Description:

Lacosamide is an antiepileptic that enhances slow inactivation of voltage-gated sodium channels, whereas carbamazepine, phenytoin and lamotrigine act mainly on fast inactivation. That difference is thought to spare normal neuronal firing while dampening the sustained depolarisation of a seizure, and it may explain why lacosamide combines reasonably with other sodium-channel drugs. It is used for focal-onset seizures, alone or as add-on, and as adjunctive therapy for primary generalised tonic-clonic seizures.

Oral bioavailability is almost complete, so tablet and intravenous doses are interchangeable one-for-one, and the injection is widely used in hospital, including in status epilepticus protocols after benzodiazepines. It has few pharmacokinetic interactions. Dizziness, diplopia and nausea are the common adverse effects. Lacosamide prolongs the PR interval, so it needs caution in conduction disease and with other PR-prolonging drugs, and an ECG is advised before starting in at-risk patients.

Sourcing notes. Generic across the US and Europe and priced competitively. It is Schedule V in the US, which brings registration and record-keeping obligations there, though most other markets do not schedule it. The tablet, oral solution and injection are separate registrations, and hospital tender demand centres on the injection. Film-coated tablets are standard manufacture.

Lacosamide — third party manufacturing & bulk supply

Lacosamide is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:

Wholesale / bulk supply Stock or scheduled supply from an existing manufacturer. The fastest route where the product is already registered in your market.
Third party manufacturing Manufactured to your specification and packed under your own brand and label — suits distributors and brand owners building a portfolio in their market.
Dossier licensing Where a CTD, EU-CTD or ACTD dossier exists it can often be licensed for filing in your name, compressing market entry from years to months.

Indicative minimum order quantity

Lacosamide is supplied as Tablets/ Oral Solution / Injectable — supplied in more than one dosage form, each with its own manufacturing economics, so the indicative MOQ is a minimum order value of USD 5,000 per product. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.

Manufacturers of Lacosamide listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.

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Frequently Asked Questions

Lacosamide is listed as Tablets/ Oral Solution / Injectable in 50 mg, 100 mg, 150 mg, 200 mg , 10 mg/mL, 200 mg/20 mL. Further strengths and pack presentations are confirmed with the manufacturer at RFQ stage.

Lacosamide is referenced against Vimpat (USA/EU), Motpoly XR (USA),. Reference brands are shown for identification only and remain the property of their respective trademark owners.

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