L-Asparaginase Suppliers & Bulk Manufacturers
Available Forms: Injection
Available Strengths: 2,500 IU, 5,000 IU, 10,000 IU vials
Reference Brands:
Category: Oncology Cancer Care
L-asparaginase is an enzyme used in acute lymphoblastic leukaemia and lymphoblastic lymphoma. E. coli-derived and Erwinia-derived asparaginase are separate products and are not interchangeable: patients who react to one are switched to the other, at different doses and schedules. Buyers must specify which is required.
Manufacture or export L-Asparaginase? List it or send an offer →
Product Description:
Asparaginase exploits a metabolic gap rather than attacking DNA. Normal cells synthesise the amino acid asparagine for themselves; lymphoblastic leukaemia cells largely cannot, and depend on what circulates in plasma. The enzyme breaks down that circulating supply, starving the leukaemic cells of a building block they cannot replace while normal tissues continue unaffected. It is one of the most selective agents in cancer medicine and a reason childhood acute lymphoblastic leukaemia is now usually curable.
It is a core component of paediatric and adult ALL protocols and is used in lymphoblastic lymphoma. Because it is a foreign protein, hypersensitivity and anaphylaxis are common and may occur without warning, and silent inactivation by antibodies can occur without any clinical reaction — which is why activity monitoring is used where available. Pancreatitis, hyperglycaemia, hepatotoxicity, and both thrombosis and bleeding from disrupted clotting protein synthesis are recognised.
Sourcing notes. Several distinct products exist — native E. coli, Erwinia chrysanthemi and pegylated forms — and they are not interchangeable: patients who react to one are switched to another, and doses and schedules differ. Buyers should state which source organism and which formulation is required. Cold chain throughout; supply has been repeatedly disrupted worldwide.
Also known as: L-asparaginasa (Spanish), asparaginase (Portuguese, French, Indonesian, Vietnamese), Asparaginase (German), asparaginasi (Italian), аспарагиназа (Russian), أسباراجينيز (Arabic), 门冬酰胺酶 (Chinese), アスパラギナーゼ (Japanese), 아스파라기나아제 (Korean).
L-Asparaginase — third party manufacturing & bulk supply
L-Asparaginase is available through PharmaTradz for wholesale and bulk supply as well as on a third party (contract) manufacturing basis. Buyers sourcing this product generally take one of three routes:
Indicative minimum order quantity
L-Asparaginase is supplied as Injection — an injectable dosage form, so the indicative MOQ is 50,000 units. Actual MOQ is confirmed by the allocated manufacturer against your pack presentation and destination market. See full supply terms for dossier formats, market availability and shelf life.
Manufacturers of L-Asparaginase listed on PharmaTradz hold site-level approvals across WHO-GMP, EU-GMP, USFDA, ANVISA and TGA, verified at onboarding.
Request a quote for L-Asparaginase →Usually answered within 48 hours, with matched manufacturers, indicative prices and document status.
Frequently Asked Questions
La L-asparaginasa es una enzima antineoplásica que se utiliza como parte de la quimioterapia combinada para tratar la leucemia linfoblástica aguda (y, según el país, el linfoma linfoblástico) en niños y adultos. Es un medicamento de uso hospitalario que administran hematólogos u oncólogos con experiencia. PharmaTradz pone en contacto a importadores con licencia, distribuidores y hospitales con fabricantes de L-asparaginasa que cuentan con certificación GMP.
A L-asparaginase é uma enzima antineoplásica usada como parte da quimioterapia combinada no tratamento da leucemia linfoblástica aguda (e, em alguns países, do linfoma linfoblástico) em crianças e adultos. É um medicamento de uso hospitalar, administrado por hematologistas ou oncologistas experientes. A PharmaTradz ajuda importadores autorizados, distribuidores e hospitais a adquirir L-asparaginase de fabricantes com certificação GMP.
La L-asparaginase est une enzyme anticancéreuse utilisée dans le cadre d'une polychimiothérapie pour traiter la leucémie aiguë lymphoblastique (et, selon les pays, le lymphome lymphoblastique) chez l'enfant et l'adulte. Elle est réservée à l'usage hospitalier et administrée par des hématologues ou des oncologues expérimentés. Grâce à PharmaTradz, les importateurs agréés, les distributeurs et les hôpitaux peuvent s'approvisionner en L-asparaginase auprès de fabricants certifiés GMP.
Related Products
Lapatinib 250 mg Tablet
Strength:
250 mg
Form: Tablets
Reference Brands: Tykerb (USA/EU)
View Details
Gemcitabine
Strength:
200 mg, 1 g, 1.4 g, 1.5 g vials
Form: Injection
Reference Brands: Gemzar (US/EU)
View Details
Eribulin Mesylate
Strength:
0.44 mg/mL
Form: Injection
Reference Brands: HALAVEN (USA/EU)
View Details
Usually answered within 48 hours | GMP documents shared before you commit
