Isoniazid Syrup Suppliers & Bulk Manufacturers

Available Forms: Oral Syrup

Available Strengths: 50 mg

Reference Brands: Generic formulations marketed under different names

Category: Respiratory Disorder

Isoniazid is used to treat tuberculosis (TB) or prevent its return (reactivation). It may be given alone, or in combination with other medicines, to treat TB or to prevent its return (reactivation).

Product Description:

Isoniazid (INH) is a first-line antitubercular antibiotic widely used for the treatment of active Mycobacterium tuberculosis (TB) infections. It has been a cornerstone of TB therapy for decades due to its potent bactericidal activity and well-established efficacy. Isoniazid functions as a prodrug that is activated by the bacterial enzyme catalase-peroxidase (KatG). Upon activation, it generates reactive radicals and adducts that specifically inhibit the synthesis of mycolic acids, which are essential components of the mycobacterial cell wall. This disruption compromises the structural integrity of the bacterium, leading to cell death.

INH is often used in combination with other antituberculosis agents to enhance therapeutic effectiveness and prevent the development of drug resistance. Its synergistic action with other medications in standard TB regimens makes it an indispensable component of multidrug therapy. Available in oral tablet and syrup formulations, INH allows for precise dosing across different patient populations, including children and adults who require flexible administration options. With a strong safety profile and proven clinical outcomes, Isoniazid remains a critical choice for healthcare professionals in the global fight against tuberculosis.