Floxuridine 500 mg Suppliers & Bulk Manufacturers

Available Forms: Injection

Available Strengths: 500 mg

Reference Brands: Generic formulations marketed under different names

Category: Oncology Cancer Care

Floxuridine is a Oncology Cancer Care product available as Injection in strengths 500 mg. It corresponds to the reference brand Generic formulations marketed under different names. Verified GMP manufacturers and suppliers on PharmaTradz offer it in bulk for import worldwide, with regulatory documentation and dossier support available on request.

Product Description:

Floxuridine, also known as 5-fluorodeoxyuridine, is an antimetabolite chemotherapy agent belonging to the pyrimidine analog class and specifically classified as a deoxyuridine. It is primarily used in oncology for the treatment of colorectal cancer, particularly for patients with liver metastases. Floxuridine is typically administered via hepatic artery infusion, allowing high local concentrations in the liver while minimizing systemic exposure. This targeted delivery has been shown to significantly improve patient quality of life and survival rates compared to standard treatments.

In addition to colorectal cancer, floxuridine may also be prescribed for kidney and stomach cancers under specialized oncology protocols. Its mechanism of action involves incorporation into DNA, inhibiting thymidylate synthase, and disrupting DNA synthesis, ultimately leading to cancer cell death. Beyond clinical applications, floxuridine is used in vitro in research to study cell proliferation, such as in Tenon’s capsule fibroblasts with short-term exposure to fluorouracil, floxuridine, and mitomycin. With its targeted delivery, high efficacy in liver metastases, and versatility in both clinical and research settings, floxuridine remains a key drug in antimetabolite chemotherapy.